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USMLE Step 1: Things I Cannot Remember > Pharmacology > Flashcards

Flashcards in Pharmacology Deck (18):
1

Drugs that cause SLE-like syndrome:

SHIPPE

  1. Sulfa drugs
  2. Hydralazine
  3. Isoniazid
  4. Procainamide
  5. Phenytoin
  6. Etanercept

2

Sulfa drugs:

  1. Probenecid
  2. Furosemide
  3. Acetazolamide
  4. Celecoxib
  5. Thiazides
  6. Sulfonamides (antibiotics)
  7. Sulfasalazine
  8. Sulfonylureas
  • Mneumonic: Popular FACTSSS

3

What is the treatment with cyanide toxicity?

Nitrate + thiosulfate, hydroxycobalamin

4

Antidote for acetaminophen toxicity:

N-acetylcysteine (replenishes glutathione)

5

Antidote for amphetamines:

NH4Cl to acidify urine

  • because amphetamines make urine more basic

6

Antidote for antimuscarinics, anticholinergics:

  • Anitmuscarinics: physostigmine salicylate
  • Anticholinergics: control hyperthermia

7

How do you reverse benzodiazepine toxicity?

flumazenil!

8

Antidote for ß-blocker toxicity:

glucagon

9

Treatment for CO poisoning:

100% O2, hyperbaric O2

10

What is used to treat Cu, Ag and arsenic poisoning?

penicillamine

11

What is used to reverse heparin?

protamine sulfate

12

What is used for Fe poisoning?

Deferoxamine, deferasirox

13

What is the treatment for Pb poisoning?

EDTA, dimercaprol, succimer, penicillamine

14

What is used for Mercury poisoning?

dimercaprol (BAL), succimer

15

What is the treatment for methemoglobinemia?

methylene blue, vit C

16

  1. What is the treatment for salicylate toxicity?
  2. What is the treatment for TCA toxicity?

  1. Salicylate toxicity: NaHCO3 (alkalinize urine), dialysis
  2. TCA toxicity: NaHCO3 (plama alkalinization)

17

How do you reverse the effects of tPA/streptokinase/urokinase?

aminocaproic acid

18

What is the treatment to reverse the effects of warfarin?

  • Immediate effect: fresh frozen plasma
  • Delayed effect: Vitamin K