Neurology Flashcards Preview

USMLE Step 1: Things I Cannot Remember > Neurology > Flashcards

Flashcards in Neurology Deck (16):
1

What passes through the cribiform plate?

CN I

2

Superior orbital fissure:

  • CN III
  • CN IV
  • CN V1 
  • CN VI 
  • Opthalmic vein
  • Sympathetic fibers

3

Foramen rotundum:

CN V2

4

Foramen ovale:

CN V3

5

Foramen spinosum:

Middle meningeal artery

6

What do CN II - VI pass through?

Middle cranial fossa — through spenoid bone

7

Optic canal:

  • CN II
  • Opthalmic artery
  • Central retinal vein

8

Internal auditory meatus:

  • CN VII
  • CN VIII

9

Jugular foramen:

  • CN IX
  • CN X
  • CN XI
  • Jugular vein

10

What does CN XII pass through?

Hypoglossal canal

11

Foramen magnum:

  • CN XI (spinal roots)
  • Brain stem
  • Vertebral arteries

12

STURGE-Weber syndrome:

Congenital, non-inherited developmental anomaly of neural crest derivatives (mesoderm/ectoderm):

  • Sporadic, port-wine Stain (CN V1/Vdistribution)
  • Tram-track calcifications
  • Unilateral
  • Retardation
  • Glaucoma; GNAQ gene (activating mutation)
  • Epilepsy

13

Tuberous sclerosis:

HAMARTOMAS: 

  1. Hamartomas (CNS & skin)
  2. Angiofibromas
  3. Mitral regurgitation
  4. Ash-leaf spots
  5. Rhabdomyoma (cardiac)
  6. (Tuberous sclerosis)
  7. autosomal dOminant
  8. Mental retardation
  9. renal Angiolipoma
  10. Seizures; Shagreen patches
  • increase incidence of subependymal astrocytomas & ungual fibromas

14

NF1 (von Recklinghausen disease):

Mutated NF1 tumor suppressor gene (neurofibromin, negative regulator of RAS) on chromosome 17:

  • ​Cafe-au-lait spots
  • Lisch nodules (iris hamartomas)
  • Cutaneous neurofibromas (neural crest derived)
  • Optic gliomas
  • Pheochromocytomas

15

von Hippel-Lindau disease:

deletion of VHL gene (tumor suppressor) on chromosome 3:

  • Hemangioblastomas (retina, brain stem, cerebellum, spine)
  • Angiomatosis
  • Renal cell carcinomas (bilateral)
  • Pheochromocytomas

16

List the adult primary brain tumors:

  1. Glioblastoma multiforme (grade IV astrocytoma
    • most common
  2. Meningioma
  3. Hemangioblastoma
  4. Schwannoma
  5. Oligiodendroma
  6. Pituitary adenoma