Pharmacology: of the neuromuscular system

Question 1

Pharmacology of the neuromuscular system

Drugs used for local anesthesia are typically named with what suffix?

Answer 1

The suffix -caine; such as lidocaine

Question 2

Pharmacology of the neuromuscular system

Pharmacological treatment of Parkinson’s Disease

Answer 2

Levodopa; precursor of dopamine

Question 3

Pharmacology of the neuromuscular system

True or false: over time, levodopa therapy becomes less effective

Answer 3

True

Best results obtained in first few years of treatment

Question 4

Pharmacology of the neuromuscular system

When would be best to schedule a PT session with a patient with Parkinson’s disease?

Answer 4

• one hour after administration when the peak effects of drug therapy
• but also during “off” effect

Question 5

Pharmacology of the neuromuscular system

Levodopa, adverse drug effects

Answer 5

• “On-off” effect: fluctuations in clinical response to levodopa
• Hypotension: particularly in patients on antihypertensives
• Other: nausea, anorexia, confusion, insomnia

Question 6

Pharmacology of the neuromuscular system

Antipsychotic drugs are typically named with what suffix?

Answer 6

The suffix -azine; such as Fluphenazine

Question 7

Pharmacology of the neuromuscular system

Antipsychotics: side effects

Answer 7

Parkinson’s like symptoms: rigidity, dyskinesia

Question 8

Pharmacology of the neuromuscular system

Meds helpful for performance anxiety, tachycardia, palpitations, tremor, sweating

Answer 8

Beta-blockers

Question 9

Pharmacology of the neuromuscular system

Drugs that end in -ine,-mine are generally what class of drug?

Answer 9

Antidepresants

Question 10

Pharmacology of the neuromuscular system

MAO inhibitors, Tricyclics, Serotonin Reuptake Inhibitors are what class of drugs?

Answer 10

Antidepressants

Question 11

Pharmacology of the neuromuscular system

Often the first type of drugs to treat hypertension

Answer 11

Diuretics

Question 12

Pharmacology of the neuromuscular system

what is the action of diuretics agents?

Answer 12

Diuretic agents increase the excretion of sodium and urine. This causes a reduction in plasma volume which decreases blood pressure.

Question 13

Pharmacology of the neuromuscular system

Drugs including thiazides, loop, and potassium-sparing agents are what class of drugs?

Answer 13

Diuretics

Question 14

Pharmacology of the neuromuscular system

Diuretic agents side effects

Answer 14

dehydration, hypotension, electrolyte imbalance, polyuria, increased low-density lipoproteins, arrhythmias

Question 15

Pharmacology of the neuromuscular system

indications of diuretic agents

Answer 15

hypertension, edema associated with heart failure, pulmonary edema, glaucoma

Question 16

Pharmacology of the neuromuscular system

Diuretic agents: implications for PT

Answer 16

Positioning changes can increase the risk of dizziness and falls due to decreased blood pressure. Monitor patients closely for signs and symptoms of electrolyte imbalance and muscle weakness or cramping.

Question 17

Pharmacology of the neuromuscular system

Dopamine replacement agents: implications for PT

Answer 17

therapists and patients attain maximal benefit from scheduling therapy one hour after administration of levodopa. Therapists must understand the debilitating effects of drug holidays and should monitor the patientʼs blood pressure frequently due to the potential for orthostatic hypotension.