Flashcards in PharmII_Exam1_pract Deck (57):
What is the drug of choice for gas gangrene?
What do PCNs combine with and inactivate?
A PCN binding protein
Are PCNs bacteriostatic or bactericidal?
What simultaneous administration prolongs duration of PCN?
99% of PCN G and V are eliminated via where?
Which antistaph PCN has poor oral adsorption?
What is the drug of choice for Listeria?
Which drug is employed prophylactically by patients with abnormal heart valves, who are to undergo oral surgery?
Are ampicillin and amoxicillin resistant to penicillinase?
Which 3 drugs are effective against indole-positive proteus?
What antipseudomonal drug can cause platelet dysfunction?
Name the most potent ureido-penicillin?
How does penicillin penetrate CSF?
Only with inflammation
The highest incidence of hypersensitivity to PCN occurs with which?
Are cephalosporins effective against penicillinase producing bacteria?
Due to increase in resistance
What class of antimicrobials are drug of choice for Klebsiella?
What are 1st gen cephalosporins active against?
Name the alternative to anti-staph PCN in penicillin allergic patients?
Name the drug of choice in surgical prophylaxis?
What are 2nd generation cephalosporins active against?
Name the 1st line of drugs for N. Gonorrheae?
Ceftriaxone - IV
Name the cephalosporins that are useful against P. aerugionsa?
What are Cetizoxime and Moxalactam active against?
(3rd gen staph)
Name two cephalosporins that are excreted through the biliary tract?
What cephalosporin group are used to treat meningitis?
Which drug is active against MRSA?
Which beta lactam antibiotic has the broadest spectrum and what is it used for?
Used in empiric therapy.
How is bacitracin administered?
What drug is used for corneal ulcers and external otitis?
What is Polymyxin restricted to treating?
Gram - bacteria.
Is polymyxin Bacteriostatic or bacteriocidal?
What is cycloserine mainly used for?
Which beta lactam is used in umbrella therapy?
What is the MOA of beta lactams?
Inhibit cell wall synthesis
Which antibiotic is highly active against Treponema pallidum(syphilis)?
Name two beta lactams that are not excreted via the kidney?
Cefoperazone and Ceftriaxone
Which drug is it safe to treat UTI in prego chicks?
Increased resistance to hydrolysis of chromosomal beta lactamse is specific to what generation cephalosporin?
Which drug is used in carriers of meningococcal infxns?
What is effective against ROcky Mountain Spotted Fever(Ricksettia)?
Which of the following is the most imp mech of resistance to tetracyclines?
Reduced permeability or increased efflux by an active transport protein pump.
What is the tetracycline of choice for SIADH?
What is the tetracycline of choice in renal insufficiency?
Doxycycline (excreted via bile).
A skin rash is a type of what........
Which drug is resistant to staphy beta-lactamases?
Which group of drugs are Effective against pseudomonas aeruginosa (gram neg)
Which drug is eliminated in the bile?
(good for renal dysfunction patients)
Which is the drug of choice for bacterial meningitis?
Does Probenecide help with NAfcillin?
NO!!! Bcaz Nafcillin is eliminated in the bile.
Which drug is used for empiric therapy?
MOA of monobactam?
Inhibits bacterial cell wall synthesis
Trt for respiratory tract infections?
This is the only monobactem
Vancomycin is given slowly through IV to treat what condition?
What is the name of the structure on the test?
What is used to treat Pseudomonas causing corneal ulcers?
What is used to treat atypical pneumonia caused by Mycoplasm?