Physiologic changes of pregnancy

Question 1

Which hormones increase in pregnancy?

Answer 1

Total T3, Total T4, thyroxine-binding globulin, TSH, PTH, prolactin

Question 2

which hormones decrease in pregnancy?

Answer 2

TSH (slightly initially)

Question 3

Which other mediators increase in pregnancy?

Answer 3

prostacyclin, thromboxane, cholesterol, ESR, plasma fibrinogen

Question 4

Which mediators decrease in pregnancy

Answer 4

Doppler S/D ratio, Hgb/Hct, Cr, BUN, total serum Calcium

Question 5

What does progesterone increase in pregnancy?

Answer 5

appetite, minute ventilation, body temp, nasal congestion, LDL, depression

Question 6

What does progesterone decrease in pregnancy?

Answer 6

Tubal mobility, uterine lining, ureteral mobility, esophageal sphincter tone, HDL

Question 7

What pulmonary values decrease in pregnancy

Answer 7

RV (residual volume), ERV (expiratory reserv volume), TLC, FRC (functional residual capacity). “take the RV down to the ER for some TLC because its Frc (EE)”

Question 8

What pulmonary values increase in pregnancy

Answer 8

inspiratory capacity, tidal volume “I see the TV”

Question 9

What are procoagulant changes in pregnancy?

Answer 9

Increase: Fibrinogen, Factors 7,8/10, vWF, Plasminogen activator inhibitor-1, Plasminogen activator inhibitor-2
Decrease: 11, 13
Stay the same: 2,5,9

Question 10

What are anticoagulant changes in pregnancy?

Answer 10

Decrease: Protein S
Stays the same: protein C, antithrombin 3