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Flashcards in Pituitary Hormones Deck (19):
1

What are the 6 hormones/factors released by the hypothalamus?

1. Gonadotrophin releasing hormone (GnRH)
2. Growth hormone releasing hormone (GHRH)
3. Somatostatin (SST)
4. Thyrotophin releasing hormone (TRH)
5. Corticotrophin releasing hormone (CRH)
6. Dopamine

2

What are the 6 hormones released by the anterior pituitary?

1. Somatotrophin (growth hormone GH)
2. Thyroid stimulating hormone (TSH)
3. Adrenocorticotropic hormone (ACTH) or corticotrophin
4. Follice stimulating hormone (FSH)
5. Leutinizing hormone (LH)
6. Prolactin

3

What does gonadotrophin releasing hormone do?

Causes the releasing of leutinizing hormone and follice stimulating hormone from the anterior pituitary

4

What does growth hormone releasing hormone do?

Causes the release of growth hormone (somatotrophin) from the anterior pituitary

5

What does samotostatin do?

Inhibits the releasing of growth hormone (somatotrophin) from the anterior pituitary

6

What does thyrotrophin releasing hormone do?

Causes the release of thyrotrophin or thyroid stimulating hormone from the anterior pituitary

7

What does corticotrophin releasing hormone do?

Causes the release of adrenocorticotropic hormone or corticotrophin

8

What does dopamine release do?

Causes the release of prolactin from the anterior pituitary

9

What does growth hormone/somatotrophin cause the release of?

IGF-1 (insulin growth like factor 1)

10

What does thyroid stimulating hormone cause the release of?

Thyroid hormones?

11

What does corticotrophin/ACTH cause the release of?

Cortisol (a glucocorticoid)

12

What does prolactin do?

Cause breast growth and milk production

13

What does leutinizing hormone act on and what do they produce?

Leydig cells - produce testosterone
Corpus leuteum - progesterone

14

What does follice stimulating hormone act on and what do they produce?

Sertoli cells and corpus leuteum - inhibin
Granulosa cells - progesterone

15

Describe the sequence of events when the hypothalamus senses stress

The hypothalamus releases corticotrophin releasing hormone which acts on the anterior pituitary to release adrenocorticotrophic hormone which acts on the adrenal cortex to produce cortisol which then goes on to produce glucose for the brain during stress

16

Describe the sequence of events when the hypothalamus senses low plasma sodium?

The hypothalamus releases CRH which acts on the anterior pituitary to release ACTH which acts on the adrenal cortex to release aldosterone

17

What are two posterior pituitary hormones that are often regarded as hypothalamic hormones?

1. Anti-diuretic hormone (vasopressin)
2. Oxytocin

18

What does vasopression do?

Increase arterial blood pressure by causing the kidneys to retain sodium and therefore water, increasing the blood volume (anti-diuretic = retains water) - urine is hypertonic

19

What does oxytocin do?

Causes contraction of smooth muscle cells to increase milk flow