Neurons and Glia Flashcards

(56 cards)

1
Q

What two things are composed of neurons and glia?

A

The brain and the spinal chord

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2
Q

What is the function of neurons?

A

Processing information and conducting electrical impusles

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3
Q

What is function of glia?

A

Mechanical and metabolic support

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4
Q

What 3 things makes up the neuron?

A
  1. Dendrites
  2. Cell body (soma)
  3. Axon
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5
Q

What are dendrites?

A

Recieve information from other neurons (the input part of the neuron)

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6
Q

What is the axon?

A

Conveys information to other nerve cells (the output part of the neuron)

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7
Q

How many axons do neurons normally have?

A

Just one that emerges from the cell body

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8
Q

What are the dendrites and axons sometimes collectively known?

A

Neurites

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9
Q

What two things make up the cell body?

A

The nucleus and the cytoplasm (perikaryon)

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10
Q

What is different between the nucleus in a neuron as compared to another cell?

A

Adult neurons do not replicate and the DNA is only involved in protein synthesis (it a blueprint for construction of neuronal components)

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11
Q

What manufactures the ribosomes of the neurons?

A

The nucleolus

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12
Q

The combination of ER and ribosomes is called the rough ER; what else can they be called?

A

Nissl bodies (seen by nissl staining)

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13
Q

Where are microtubules found in the neruon and what are they responsible for?

A

The dendrites, cell body and axon and are responsible for transporting packaged proteins

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14
Q

What else are the microtubules involved in that provides support for the neruon?

A

The form the cytoskeleton

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15
Q

What are lipofucin bodies in neurons?

A

The scrap yard of the neuron which contains the waste products of the old cells

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16
Q

What cellular components have a similar function in neurons as they do in normal cells?

A

Ribosomes, the golgi apparatus, mitochondria and lysosomes

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17
Q

What do the dendrites mainly contain in terms of cellular components?

A

Mitochondria and free ribosomes

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18
Q

What the connections with other neurons formed in the dendrites known as?

A

Synapses

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19
Q

What specialised structures of the dendrites and the synapses usually made on?

A

Spines

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20
Q

What are the four parts of the axon?

A
  1. The axon hillock
  2. The axon proper
  3. Axon collaterals
  4. The axon terminals
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21
Q

What the axon hillock?

A

The part of the axon that emerges from the cell body and contains lots of voltage gated ion channels to generate action potentials

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22
Q

What is the axon proper?

A

The main part of the axon

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23
Q

What is the axon collaterals?

A

The branches of the axon that go off to numerous locations

24
Q

What is the axon terminals?

A

Swellings (boutons) that form synpases

25
Why is important that axons have a transport for proteins?
Because they dont contain ribosomes to make their own proteins
26
How does transport to the axon occur and what is this known as?
Along microtubules in axoplasmic transport
27
How fast is axoplasmic transport?
Very fast - 1000mm/day
28
What is axoplasmic transport towards the cell body called?
Retrograde transport
29
What is axoplasmic transport away from the cell body called?
Anterograde transport
30
Why would retrograde transport be useful?
To get rid of waste products back to the soma for them to be broken down
31
What are the 5 ways to classify neurons?
1. Number of neurites 2. Shape 3. Connections 4. Axons 5. Neurotransmitters
32
What are the three types of neurons classified under number of neurites?
Unipolar, bipolar and multipolar
33
What is an example of a unipolar neuron?
Sensory neurons
34
What is an example of a bipolar neuron?
That ones connecting the rods and cones in the eyes to the brain
35
What kind of shapes can neurons have?
Pyramidal, stellate
36
What 3 types of neurons are there in the classification based on connections?
1. Primary sensory neurons 2. Motoneurons 3. Interneurons
37
What are primary sensory neurons?
Neurons that form connection with sensory surfaces (skin, retina etc)
38
What are the motoneurons?
Neurons that form connections with muscles
39
What are interneurons?
Neurons that form connections with other neurons
40
What are the two types of neurons classified under axons?
1. Golgi type 1 (long axons) | 2. Golgi type 2 (local axons)
41
What are examples of three neurons classified under neurotransmitters?
1. Cholinergic neurons (release acetylcholine) 2. Glutamergic neurons (glutamide) 3. Peptitergic neurons (peptides)
42
How much of the brain is composed of glia?
90%
43
What are the three classes of glia?
1. Astrocytes 2. Oligodendrocytes 3. Microglia
44
What are astrocytes and oligodendrocytes sometimes collectively known?
Macroglia
45
What is the most numerous type of glial cells?
Astrocytes
46
Name two functions of the astrocytes:
1. Repair in damaged neurons | 2. Regulate flow of ions and molecules in the extracellular fluid
47
How many organelles do astrocytes contain?
Very few
48
How many organelles do oligodendrocytes contain?
Lots
49
What is the main function of oligodendrocytes?
They make myelin that forms a sheath around the axons of neurons?
50
What is myelin composed of?
Lipids
51
The myelin sheath around the axon is not continuous; what are the gaps in it called?
The nodes of ranvier
52
What do the Node of Ranvier do?
Increase the speed of electrical conduction of the axon
53
In what part of the nervous system do oligodendrocytes make myelin?
The central nervous system
54
What makes myelin in the peripheral nervous system?
Schwann Cells
55
What are microglia?
Phagocytes that remove waste
56
How many neurons in the CNS nie every day that need to be removed by microglia?
100,000