PLACENTA Flashcards

1
Q

how is placenta form

A

when maternal blood supply. has been accessed

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2
Q

what happens when synctiotrophoblastts invade maternal blood vessels

A

lacunae form

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3
Q

chorionic villi form

A
  • proliferation of cytotrophoblast
  • growth of chorionic mesoderm
  • ## blood vessel development
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4
Q

what happens to primary chorionic villi around day 13 post fertilisation

A

cords or asses of cytotrophoblasts growing into lacunae within synctiotrophoblass

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5
Q

what day is secondary chorionic villi

A
  • days 16
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6
Q

when is teritary chorionic villi

A

end of third week development

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7
Q

nam

A

tertiary villi early

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8
Q

name

A

tertiary villi mature

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9
Q

maternal component of placenta - decidualisatin

A

after implanation of blastocyst

stroma cells become large round decidual cells

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10
Q

regions of decidua

A
  • decidua basalis
  • decidua capsularis
  • decidua parietalis
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11
Q

what happens by the end of 3 month for placenta decidualisation

A

gestation
decidua capsularises fuses with decidua parietalis of opposite wall

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12
Q

which layers of the endometrium form decidua

A

all but the deepest layer

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13
Q

what does decidua shed with

A

placenta at birth

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14
Q

what is a cytotrophoblastic shell

A

complete shell around synctiotrophoblast - attaches to endometrium

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15
Q

what do maternal blood vessels communicate with

A

through shell

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16
Q

what happens to the villi during pregnancy

A

mature - smaller in diameter

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17
Q

what happens to the cytotrophoblast during pregnancy

A

discontinues

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18
Q

plates in mature placenta

A

basal plate
chorionic plate

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19
Q

what does basal form from in mature placenta

A

decidual basalis

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20
Q

what does chorionic plate form from in mature placenta

A

embryological origin

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21
Q

what is the blood supply to the placenta

A

spiral arteries

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22
Q

what is the placental barrier

A

seperation of maternal and fetal blood

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23
Q

describe the diameter of the placental barrier

A

very thin by 4 months > allow exchange of products across placenta

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24
Q

functions of placenta

A
  • metabolism
  • transport
  • barrier function
  • immunological function
  • endocrine function
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25
when does placenta take over from
corpus leutrum 8 weeks gestation
26
what does adrenal cortex provide
androgens
27
when is human chorionc gonadotropins produced from
6 days post fertilisatin maintains corpus leutrum < maintains endometrium > and pregnancy
28
placental problems
- placenta previa - placenta abruption
29
what is placenta previa
covers internal os of cervix
30
what is placenta abruption
comes away from uterine wall
31
what is pre-eclampsia
pregnancy induced hypertension + protenuria
32
what is the treatment of pre-eclampsia
delivery of placenta
33
what is the cause of pre-eclampsia
unknown cause - probkems with endometrial blood vessel problem
34
what cell secretes HCG
trophoblast cells
35
which of the cells in the endometrium are mitoticaly active
cytotrophoblast
36
what fuses with synctiotrophoblasts
cytotrophoblasts
37
what is not mitotically active
synctiotrophoblasts
38
what invades into maternal blood vessels
synctiotrophoblasts
39
what happens after synctiotrophoblasts invade into maternal blood vessels
lacunae form
40
what happens at the Day 11-12 development
closing plug formed implanted embryo within wall of endometrium
41
list the types of villi
primary secondary and tertiary
42
when does primary chorionic villi occur
around D13 post fertilisation
43
what happens at the primary chorionic villi
two distinct layers of synctiotrophoblasts and one layer of cytotrophoblasts
44
when is secondary chorionic villi formed
D16
45
list the prominent layers of secondary chorionic villi
inner layer cytotrophoblast outer layer synctiotrophoblast
46
what is primary villi invaded by
loose ct from chorion
47
when is tertiary chorionic villi formed
end of 3rd week development
48
when do blood vessels grow in villi
secondary and tertiary chorionic villi
49
what can you see in mature tertiary villi
synctial knots
50
what is the maternal component of placenta
decidualisation
51
when does decidualisation occur
after implantation of blastocyst (8-10 days of embryo development)
52
what happens to the stroma cells in decidualisation
they become large round decidual cells
53
list the regions of decidua
- decidua basalis - decidua capsularis - deciduda parietalis
54
where is decidua capsularis located
between implantation site and lumen
55
where is decidua parietalis
remaining endometrium
56
when does decidualisation happen
by end 3rd month gestation
57
what happens by end of 3rd month gestation in decidualisation
decidua capsularis fuses with deciduda parietalis of opposite wall
58
what happens when decidua capsularises fuses with dec. parietalis
obliteration of uterine cavity
59
what shed with placenta at birth
decidua
60
what shell attaches to endometrium
cytotrophoblastic shell
61
how do maternal blood vessels communicate
through shell of cytotrophoblastic shell
62
is growth of villi continuous throughout pregnancy
yes
63
where do stem villi or anchoring villi grow
into maternal side of placenta > basal plate
64
what is the size of villi during pregnancy
mature, smaller in diameter
65
what discontinues during pregnancy
cytotrophoblast
66
how are synctial knots formed
synctiotrophoblast nuclei gathered in clusters
67
list the features of mature placenta
basal plate > from decidual basalis chorionic plate cotyledons
68
what divides fetal part of placenta
cotyledons - 15-25
69
blood supply to placenta
spiral arteries
70
what does the placental barrier seperate
materal and foetal blood
71
what is the thickness or thinness of placental barrier
very thin by four months
72
function of the thinness of placental barrier by 4 months
allows exchange of products across placenta
73
what does placenta take over from
corpus luteum 8 weeks gestation
74
when are human chorionic gonadotrophins produced from
day 6 post fertilisation
75
what does the human chorionic gonadotrophins maintains
corpus luteum endoemtrium pregnancy
76
what is human chorionic gonadotrophins secreted b y
synctiotrophoblasts
77
what is relaxin from
decidual cells
78
what does relaxin do
softening of cervix and pelvic ligaments
79
what are the other hormones secreted by placenta
IGF-1 IGF-II endothelial growth factors leptin
80
treatment of pre-eclampsia
delivery of placenta
81
what secretes hcg
trophoblastic shell