Plasticity, Theories, and Basic Variables Flashcards
(95 cards)
What is plasticity
The ability to show neural modifiability from short term changes in efficiency/strength of synaptic connections to long term structural changes in organization/number of connection of neurons
True or False:
Plasticity is experience dependent reorganization
True
What are the fundamentals of plasticity (5)
- Plasticity involves a variety of processes and structures that take place throughout lifetime
- Plasticity has a clear age dependent determinant
- Plasticity occurs under two conditions
- Plasticity is influenced by environment
- Plasticity is a two way street
What are the 2 conditions under which plasticity occurs
- Typical brain development
2. Adaptive mechanism to injury
What does it mean that plasticity is a two way street
If you don’t use it you lose it
When does plasticity occur (3)
- Beginning of life (critical period)
- Throughout adulthood (following critical period)
- Damage (compensations and relearning
How does plasticity lead to learning (2)
- Changes in internal structures of neurons at synapses
2. Increased number of synapses between neurons
Where do short term changes usually occur
At the level of the synpase
What are the 2 types of plasticity
- Functional plasticity
2. Structural plasticity
What is functional plasticity
The ability of the brain to change a functional task to another area following damage
What is structural plasticity
The ability of a structure to change over time
Characteristics of acquisition of skills occur in infants during critical periods (3)
- Info is unregulated
- The brain is always on
- Synaptic formation is constantly occurring
Why is the info unregulated and the brain always being on
The infant does not know what to pay attention to so they take everything in leading too mass synapse formation
When do critical periods occur
Birth to 2 years
Characteristics of acquisition of skills occur in older children/adults (3)
- Generation of reliable/coordinated responses
- Increase power of off
- Synaptic pruning
True or False:
Learning and recovery of function is a continuum
True
What is function
Complex activity directed at performance of a task
What is recovery
Re-acquisition of movement skills lost through injury
What is recovery of function impacted by (5)
- Age
- Characteristics of lesion
- Pre-injury factors
- Post-injury factors
- Neurotrophic factors
What are neurotrophic factors
Proteins that are responsible for growth in the nervous system
What levels can plasticity occur at (6)
- Brain level
- Network level
- Intercellular level
- Intracellular level
- Biochemical level
- Genetic level
Following injury we may see what (4)
- Denervation supersensitivity
- Unmasking of silent synapses
- Neural regeneration
- Collateral sprouting
What is denervation supersensitivity
Increased sensitivity after denervation (demyelination)
What is unmasking of silent synapses
Immediate reorganization secondary to “unmasking” of previously non functional, nearby synaptic connections