Pre-malignant And Malignant Of Cervix

Question 1

Where do the squamous and columnar epithelial meet

Answer 1

Squamocolumnar Junction (SJC)

Question 2

Where is the most common site for abnormal cells to develop

Answer 2

Squamocolmnar junction

Question 3

What type of cyst develop from a blockage of glandular cleft by squamous metaplasia

Answer 3

Nabothian cyst

Question 4

What is the treatment for a nabothian cyst

Answer 4

No treatment needed

Question 5

What is a pedunculated cyst that can be composed of any type of cervical cells and is benign

Answer 5

Cervical polyps

Question 6

What is the treatment for a cervical polyp

Answer 6

Excised and sent for pathology

Question 7

What are the two benign lesions of the cervix

Answer 7

Nabothian cyst

Cervical polyp

Question 8

Name the term

Abnormal increase in size of each cell

Answer 8

Hypertorphy

Question 9

Name the term

Abnormal increase in number of cells (but normal type and locations)

Answer 9

Hyperplasia

Question 10

Name the term

Replacement of one mature cell type with another

Answer 10

Metaplastia

Question 11

Name the term

Replacement of mature cells with immature cells

Answer 11

Dysplasia

Question 12

Name the term

New growth, abnomral uncoordinated, excessive cell growth

Answer 12

Neoplasia

Question 13

Name the term

Undifferentiated neoplasia, primitive, lack of specialization of any particular cell line

Answer 13

Anaplasia

Question 14

What is a disordered growth and development of epithelial lining of cervix

Answer 14

Cervical intraepitheilial neoplasia

Question 15

What is abnormal growth of lower 1/3 of epithelial lining

Answer 15

CIN 1

Question 16

What is abnormal growth of lower 2/3

Answer 16

CIN2

Question 17

What is abnormal growth of > 2/3

Answer 17

CIN 3

Question 18

Abnormal growth full thickness

Answer 18

Carcinoma in situ

Question 19

How do you evaluate cytology of squamous intraepitheial lesions

Answer 19

Pap smear

Question 20

What classification is more associated with transient HPV infection

Answer 20

Low grade squamous intraepithelial lesion

Question 21

What classificiation is more likely associated with persistent HPV infection

Answer 21

High grade squamous intraepithelial lesion

Question 22

What is the primary causative factor for developing CIN and cervical cancer

Answer 22

HPV

Question 23

Do condoms prevent all transmission of HPV

Answer 23

No due to scrotal labia transmission

Question 24

What are the most common types of HPV to cause cancer

Answer 24

16 and 18

Question 25

What are the two low risk HPV types to cause cancer, but more likely to cause genital warts

Answer 25

6 and 11

Question 26

How do you treat HPV

Answer 26

Most spontaneously resolve on their own

Question 27

How do you diagnose HPV

Answer 27

PAP smear

Question 28

At what age would you think about screening for HPV

Answer 28

30-65

Question 29

What two solutions can you use on colposcopy that can help find lesions

Answer 29

``` Acetic acid (vinager) Lugol's solution (iodine) ```

Question 30

How do you treat an CIN 1

Answer 30

Monitor

Question 31

How do you treat a CIN 2 or 3

Answer 31

Ablation or excision

Question 32

What type of ablation is good for small lesions that are visable on the cervix

Answer 32

Cryotherapy and electrocautery

Question 33

What type of ablation is used for large lesions

Answer 33

Laser

Question 34

What type of treatment can be both diagnostic and therapeutic

Answer 34

Excision

Question 35

What is the most common type of cervical cancer

Answer 35

Squamous cell cancer

Question 36

What symptoms can one have who has cervical cancer

Answer 36

Abnormal bleeding is most common, pelvic pain and pressure, leukorrhea

Question 37

How do you diagnose cervical cancer

Answer 37

Based on Pap smear

Question 38

Where are you worried about mets going to with cervical cancer

Answer 38

Lungs get a CXR

Question 39

What is the treatment for cervical cancer

Answer 39

CIS or IA1 total hysterectomy

Question 40

When does one need to follow up with cervical cancer

Answer 40

Every 4 months for 2 years then Every 6 months for 3 years then Annually

Question 41

What can be given for prevention of cervical cancer

Answer 41

HPV vaccine

Question 42

What are the FDA approved vaccines for prevention of cervical cancer

Answer 42

Cerarix Gardasil Gardasil 9

Question 43

What HPV types does Cervarix cover

Answer 43

16 and 18

Question 44

What HPV types does Gardisil cover

Answer 44

6, 11, 16 and 18

Question 45

What HPV types does Gardisil 9 cover

Answer 45

6, 11, 16, and 18 along with many more types