Pre-malignant And Malignant Of Cervix Flashcards

1
Q

Where do the squamous and columnar epithelial meet

A

Squamocolumnar Junction (SJC)

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2
Q

Where is the most common site for abnormal cells to develop

A

Squamocolmnar junction

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3
Q

What type of cyst develop from a blockage of glandular cleft by squamous metaplasia

A

Nabothian cyst

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4
Q

What is the treatment for a nabothian cyst

A

No treatment needed

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5
Q

What is a pedunculated cyst that can be composed of any type of cervical cells and is benign

A

Cervical polyps

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6
Q

What is the treatment for a cervical polyp

A

Excised and sent for pathology

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7
Q

What are the two benign lesions of the cervix

A

Nabothian cyst

Cervical polyp

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8
Q

Name the term

Abnormal increase in size of each cell

A

Hypertorphy

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9
Q

Name the term

Abnormal increase in number of cells (but normal type and locations)

A

Hyperplasia

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10
Q

Name the term

Replacement of one mature cell type with another

A

Metaplastia

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11
Q

Name the term

Replacement of mature cells with immature cells

A

Dysplasia

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12
Q

Name the term

New growth, abnomral uncoordinated, excessive cell growth

A

Neoplasia

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13
Q

Name the term

Undifferentiated neoplasia, primitive, lack of specialization of any particular cell line

A

Anaplasia

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14
Q

What is a disordered growth and development of epithelial lining of cervix

A

Cervical intraepitheilial neoplasia

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15
Q

What is abnormal growth of lower 1/3 of epithelial lining

A

CIN 1

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16
Q

What is abnormal growth of lower 2/3

A

CIN2

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17
Q

What is abnormal growth of > 2/3

A

CIN 3

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18
Q

Abnormal growth full thickness

A

Carcinoma in situ

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19
Q

How do you evaluate cytology of squamous intraepitheial lesions

A

Pap smear

20
Q

What classification is more associated with transient HPV infection

A

Low grade squamous intraepithelial lesion

21
Q

What classificiation is more likely associated with persistent HPV infection

A

High grade squamous intraepithelial lesion

22
Q

What is the primary causative factor for developing CIN and cervical cancer

A

HPV

23
Q

Do condoms prevent all transmission of HPV

A

No due to scrotal labia transmission

24
Q

What are the most common types of HPV to cause cancer

A

16 and 18

25
Q

What are the two low risk HPV types to cause cancer, but more likely to cause genital warts

A

6 and 11

26
Q

How do you treat HPV

A

Most spontaneously resolve on their own

27
Q

How do you diagnose HPV

A

PAP smear

28
Q

At what age would you think about screening for HPV

A

30-65

29
Q

What two solutions can you use on colposcopy that can help find lesions

A
Acetic acid (vinager) 
Lugol's solution (iodine)
30
Q

How do you treat an CIN 1

A

Monitor

31
Q

How do you treat a CIN 2 or 3

A

Ablation or excision

32
Q

What type of ablation is good for small lesions that are visable on the cervix

A

Cryotherapy and electrocautery

33
Q

What type of ablation is used for large lesions

A

Laser

34
Q

What type of treatment can be both diagnostic and therapeutic

A

Excision

35
Q

What is the most common type of cervical cancer

A

Squamous cell cancer

36
Q

What symptoms can one have who has cervical cancer

A

Abnormal bleeding is most common, pelvic pain and pressure, leukorrhea

37
Q

How do you diagnose cervical cancer

A

Based on Pap smear

38
Q

Where are you worried about mets going to with cervical cancer

A

Lungs get a CXR

39
Q

What is the treatment for cervical cancer

A

CIS or IA1 total hysterectomy

40
Q

When does one need to follow up with cervical cancer

A

Every 4 months for 2 years then
Every 6 months for 3 years then
Annually

41
Q

What can be given for prevention of cervical cancer

A

HPV vaccine

42
Q

What are the FDA approved vaccines for prevention of cervical cancer

A

Cerarix
Gardasil
Gardasil 9

43
Q

What HPV types does Cervarix cover

A

16 and 18

44
Q

What HPV types does Gardisil cover

A

6, 11, 16 and 18

45
Q

What HPV types does Gardisil 9 cover

A

6, 11, 16, and 18 along with many more types