Primary Sclerosing Cholangitis (PSC)

Question 1

Primary Sclerosing Cholangitis (PSC)

Answer 1

bile ducts, both inside and outside the liver, become inflamed and scarred. This leads to a build up of bile in the liver, therefore damaging the liver cells - leading to cirrhosis.

Question 2

Primary Sclerosing Cholangitis - Associations:

Answer 2

UC (4% of patients with UC have PSC
80% of patients with PSC have UC)
HIV.

Question 3

Primary Sclerosing Cholangitis - Symptoms:

Answer 3

This is usually asymptomatic

but there may be:

Fatigue
Itchy Skin

Question 4

Primary Sclerosing Cholangitis - Investigations:

Answer 4

MRCP/ERCP

Liver Biopsy

Question 5

Primary Sclerosing Cholangitis - Treatment:

Answer 5

Liver Transplant

Biliary Stent