Principles of Neuroscience Lecture 26 Fear Flashcards

0
Q

Describe how there is development and change of emotion (and fear) over the course of one’s life

A

4-6 robbers, kidnappers
6-10: bodily harm
10-11: social fears

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1
Q

Describe how the cat lobotomy study helped to determine which areas were important for fear

A

When the hypothalamus was removed, there was no evidence of fear

When the hypothalamus was partly removed, and the cerebral cortex completely removed, there was sham rage.
The cerebral cortex is required for ‘directing’ rage at something

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2
Q

What are some common disorders associated with dysfunction of emotional systems

A
Panic disorder
Panic attacks
Obsessive compulsive
PTSD
Phobias
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3
Q

What are the symptoms of panic attacks

A

Shivering
Accelerating heart rate
Sweating
Nausea

Thus motor, cognitive, autonomic, thermoregulatory affected

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4
Q

Differentiate between volitional and emotional displays of emotion

A

Eg. Facial expressions
There are social smiles and also the smile that is the result of facial muscles moving when we hear a joke for example

The two are distinguishable, and an individual may be able to produce one and not the other

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5
Q

Which area of the brain has a main role in emotional expression ?

A

The hypothalamus

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6
Q

Differentiate between the medial and lateral inputs of emotional and volitional emotional behaviour

A

Medial: visceral representation of emotion, gain setting
Eg. Increased heart rate, butterflies in stomach

Lateral: somatic representation of specific emotional behaviours eg. Facial expression, waving arms about etc.

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7
Q

What is the function of the limbic system, and what areas comprise it?

A

Amygdala
Hippocampus
Hypothalamus

This area is related to descending control of emotion via the hypothalamus and memory of the fear

Connections from the limbic lobe to the Orbital and Medial PFC: planning of behaviour according to one’s emotional response to a stimulus;

  • avoiding a punisher or
  • seeking the reward
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8
Q

When is the amygdala activated?

A

When we receive a primary enforcer fear stimulus, such as a foot shock or something that we are evolved to be afraid of

Eg. When we see a face that we consider untrustworthy

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9
Q

What goes on in the orbital and medial prefrontal cortex?

A

Generation of outcomes of complex situations especially evil, dark ideas

Planning of behaviour according to our emotional response to a stimulus

Implicit motor actions in response to stimuli that evoke emotions

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10
Q

Which areas of the brain does the amygdala interact with?

A
  1. Olfactory bulb
  2. Hypothalamus and brain stem
    Autonomic response to a stimulus that elicits a certain emotion
    Eg. Increased heart rate, butterflies in stomach, gut feelings
  3. Orbital and medial prefrontal cortex
    Structuring of behaviour according to the emotional response to a stimulus
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11
Q

Describe the process of fear conditioning with reference to a particular study.
What is the mechanism of fear learning?

A

The rat in a cage receiving foot shocks

The mechanism is long term potentiation

When the rat received a shock at the same time as a musical tone was heard, the connection between the neuron in the amygdala and the input from the auditory tract would be strengthened

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12
Q

Describe the effect of damage to the amygdala

A

No longer reacts to a face that normally generates fear in other individuals

Unable to draw a face depicting the emotion of fear

All other emotions are intact

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13
Q

What is required for awareness of emotion?

What do problems in this area lead to?

A

Amygdala and hippocampus

Panic disorders due to dysfunction of this interaction

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14
Q

How does fear affect pain perception?

A

In extremely scary situations, pain is not felt

Fear over rides the perception of pain

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15
Q

Describe one of the treatments for fear disorders, and explain the mechanism

A

Benzodiazepine

This binds to and enhances the effect of GABA receptors

These are inhibitory receptors that decrease the activity of the neurons

Thus, the individual experiences a sedative, sleep inducing, anxiolytic effect

16
Q

In panic disorder, what can be observed in brain scans?

A

Reduced activity of GABA in the brain –> increased excitability