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Flashcards in Prions Deck (10):
1

infectious protein particles that are resistant to chemicals radiation and heat are known as

prions

2

how does a normal protein become a prion

they are misfolded

3

PrPC refers to wild type or misfolded

wild type

4

PrPSc refers to

mutant (misfolded)

5

is the PrPSc or PrPC resistant to proteases ?

PrPSc

6

when PrPSc aggregates it forms deposits on brain called

amyloid rods (fibrils)

7

Prions cause slow neurodegenerative disease t/f

true

8

what are the 4 kinds of transmissible spongiform encephalopathies found in humans

1. Creutzfeldt Jakob Disease
2. Variant CJD - from infected meat
3. Fatal Familial Insomnia
4. Kuru

9

What are the 2 kinds of transmissible spongiform encephalopathies found in animals

1. Scrapies - in sheep and goats
2.Mad cow disease - cattle

10

The harder you work

*the better your luck* ;)