Protein Flashcards
(59 cards)
8 Protein uses in the body
1) Antibodies/Immune
2)Hormones
3)Enzymes
4)Structural and Mechanical (actin/myosin)
5)Fluid Balance
6)Channels and Pumps
7) Acid-Base Balance
8)Transport
What 3 things contribute to the AA pool?
1)Body and Protein Degradation
2)Dietary proteins
3)Synthesis of NEAA (liver)
What is the fate of the AA pool
Anabolism (build tissues)
Catabolism (breakdown)
2 Anabolism fates of AA
1)Protein (hormones, enzymes, protein)
2)Nitrogenous Compounds
(Neurotransmitters, Niacin, Creatine, Heme)
Catabolism of AA fate x3
1) Ketone bodies, Fatty Acids
2)Urea, CO2, H2O
3)Glucose/Glycogen
Most AA catabolism occurs how?
Urea, Co2, H2O
-Need to excrete N from body
BCAA
Leucine
Isoleucine
Valine
What contributes to the AA pool
BCAA
EAA
NEEA
Endogenous AA
EAA x9
Histidine
Isoleucine
Leucine
Lysine
Methionine
Phenylalanine
Threonine
Tryptophan
Valine
Estimate Average Requirement (EAR)
The daily intake value that is estimated to meet the nutrient requirements of half of the healthy indv in the pop
Recommended Dietary Allowance (RDA)
The daily dietary intake level that is sufficient to meet the nutrient requirements of 97-98% of healthy individuals in a population
Adequate Intake (AI)
The AI is expected to meet or exceed the needs of most individuals in the population
Tolerable Upper Intake Level (UL)
The highest daily nutrient intake level likely to pose no risk of adverse health effects to almost all indv in a population
How do you calculate AI/Recommended daily allowance?
EAR + 2 SD
RDA for protein in Canada?
0.8-0.9 protein/kg/day
What is issue with research for RDA
RDA is based on whole-body data
-Everyone is different and difficult to measure
Skeletal muscle is a critical organ and is linked with? x5
- Mortality or Mobility
- Diabetes (Insulin resistance)
- Recovery from Surgery
- Disability
- Athletic Performance
Skeletal muscle takes up what percentage of glucose from the body?
80%
What is considered the primary whole-body insulin resistance?
skeletal muscle
To increase skeletal muscle mass what should you do
Increase resistance exercise and AA
How does RE increase muscle mass
Increases muscle sensitivity
-MPB Breakdown = Same but increase MPS
-increease muscle working towards that area
Does EAA or NEAA drive increases in MPS
EAA
The study showed when EAA and NEAA combined compared to EAA showed same increases
What is Hyperaminoacidemia
Too many AA (protien) reaches saturation
MPS is elevated how many hours following the cessation of resistance exercise
48 hours for it to not show synthesis anymore with the effects of RE