Flashcards in Protein Structure And Function Deck (11)
What is the definition of protein?
Long chain of covalently linked amino acids
Linked together via a polypeptide bond
What dictates the non-covalent bonds?
The different amino acid side chains
The covalent bonds gives the chain ______ and _____
Non covalent bonding _________ ______
Flexibility and rotation
What pushes hydrophobic molecules together and arranges proteins into compact conformations?
What helps the protein fold correctly and bind to the correct proteins?
Improperly folded proteins result in what?
Alzheimer’s ( protein aggregates that form beta amyloid plaques)
Huntington’s (inclusion bodies are formed)
Creuzfeld-Jakobs disease (infectious protein (prion disease))
Parkinson’s (lewey bodies formed, aggregate into amyloid fibrils)
What are the three folding patterns?
What are the four different levels of protein organization?
What makes up a primary structure?
Amino acid sequence
What makes up a secondary structure of protein?
Alpha helix and beta sheets