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MCAT Biology > Proteins > Flashcards

Flashcards in Proteins Deck (9):
1

What are the 4 levels of protein structure?

Primary, Secondary, Tertiary, Quaternary

2

What is the 1st level of protein structure?

Primary: refers to the amino acid sequence.
Amino acids are linked linearly by peptide bonds

3

What is the 2nd level of protein structure?

Secondary: refers to the conformation adopted by local regions of the protein chain.
Chains fold into alpha helixes or beta sheets through hydrogen bonding

4

What is the 3rd level of protein structure?

Tertiary structure.
Additional folding caused by hydrophobic (interior) and hydrophilic (exterior) interactions

5

What's is the 4th level of protein structure?

Quaternary structure. Consists of more than one chain. Subunits are joined together by noncovalent bonds

6

What determines the structure of a protein?

The amino acid sequence determines the 3D structure and all of its other properties

7

What are the interactions that help create protein tertiary structure?

1) hydrogen bonding, 2) disulfide bonds, 3) hydrophobic/hydrophilic interactions, 4) ionic interactions, 5) Van der Walls forces, and 6) proline turns

8

What are the protein dewatering agents?

-Acid
-Heat
-Urea
-Mercaptoethanol

9

What do you need to do to re-nature a protein?

Remove the dewatering agent