Protozoa Flashcards

1
Q

Produces cytopathic effect of E. Histolytica

A

Cysteine proteases

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2
Q

Mediates adherence of entamoeba

A

Lectin

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3
Q

Flask shaped colon ulcers

Dysentery without fever

A

Amebic colitis

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4
Q

Most common extraintestinal form of entamoeba

Anchovy sauce aspirate

A

Amebic liver abscess

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5
Q

Ttt for cyst carrier state of entamoeba

A

Diloxanide furoate

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6
Q

Luminal agents for entamoeba

A

Diloxanide furoate
Iodoquinol
Paromomycin

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7
Q

Falling leaf motility

A

Giardia lamblia

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8
Q

Variant surface protein

A

Giardia lamblia

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9
Q

Villous flattening, disruption of cytoskeleton Ultimately leads to enterocyte apoptosis

A

Giardia

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10
Q

Excessive flatus
Foul smelling diarrhea
Chronic: steatorrhea

A

Giardia

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11
Q

Acid fast parasite autoinfection in IS pts, self limited nonbloody diarrhea

A

Cryptosporidium parvum

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12
Q

Ttt for crytosporidium

A

Nitazoxanide

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13
Q

Infective and diagnostic stage of cryptosporidium

A

Thick walled oocysts

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14
Q

Pear shaped flagellated trophozoites

A

Trichimonas vaginalis

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15
Q

Greenish vaginal discharge

A

Trichomoniasis

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16
Q

Strawberry cervix
Ectocervicitis
Punctate hemorrhage

A

Trichomoniasis

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17
Q

Ttt for trichomoniasis

A

Metronidazole 2 g

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18
Q

Transmitted thru anopheles

A

Plasmodium

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19
Q

Infective stage of plasmodium

A

Sporozoites

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20
Q

Diagnostic stage of plasmodium

A

Trophozoites (ring forms)

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21
Q

Provides immunity to malaria

A

RBC defects

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22
Q

Banana shaped gametocyte

A

P. falciparum

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23
Q

Large round gametocyte

A

P. vivax

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24
Q

Recurrence of symptoms after temp abatement 2-4 weeks

A

Recrudescence

Falciparum, malariae

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25
Return of disease after cessation, reactivation of hypnozoites (1-6 months)
Relapse | Vivax, ovale
26
Benign quartan
P. malariae
27
Malignant tertian
P. falciparum
28
Highest yield in blood samples for plasmodium
During fever or 2-3 hrs after peak
29
Punctate granulations in RBC
Schuffner - ovale, vivax
30
Coarse granulations in RBC
Maurer - falciparum
31
Fine granulations in RBC
Ziemann - malariae
32
Malarial or durck granulomas
Cerebral malaria
33
Intravascular hemolysis Massive hemoglobinuria ARF
Blackwater fever | P. falciparum
34
Septic shock due to plasmodium
Algid malaria
35
Endemic areas for plasmodium
Palawan Kalinga apayao Ifugao Agusan del sur
36
Areas with Chloroquine resistant malaria
Palawan Davao del norte Compostela valley
37
Tissue schizonticide (liver) and gametocide (blood)
Primaquine
38
Blood schizonticide
Chloroquine | Quinine
39
Sporonticide in mosquito
Proguanil | Pyrimethamine
40
Ttt for Chloroquine resistant malariae
Mefloquine + doxycycline
41
Eradication of hypnozoites
Primaquine
42
Severe or pregnant
Chloroquine or quinine
43
Vivax and ovale ttt
Chloroquine + primaquine
44
Prophylaxis for plasmodium
Chloroquine
45
Prophylactic for areas with chloroquine resistance
Malarone | Mefloquine
46
Prophylaxis for MDR resistant falciparum
Doxycycline
47
Definitive host: domestic cat
Toxoplasma gondii
48
Preferred dx test for toxoplasmosis
IgM antibody
49
Intracranial calcifications
Congenital toxoplasmosis
50
Ttt for toxoplasmosis
Sulfadiazine + pyrimethamine
51
Transmitted by reduviid bug (triatoma)
Trypanosoma cruzi
52
Most often and severely affected tissue by t. Cruzi
Cardiac muscle
53
Periorbital edema in acute chagas dse
Romana's sign
54
Ttt of chagas dse
Nifurtimox
55
Dx stage of t. Cruzi and t. Bruceii
Trypomastigotes in blood
56
Transmission by tsetse fly (glossina) bite
Trypanosoma brucei
57
Remarkable antigenic variation | Cyclical fever spike every 2 weeks
Trypanosoma bruceii
58
Enlargement of post cervical LN
Winterbottom's sign | T. Bruceii
59
Hyperesthesia in t. Bruceii
Kerandel's sign
60
Plasma cells with cytoplasmic immunoglobulin globules
Mott cells in t. Bruceii encephalitis
61
Ttt for t. Bruceii
Suramin | Melarsoprol
62
Transmission by bivalve molluscs and fish from red tide
Dinoflagellates
63
Granulomatous amebic encephalitis
Acanthamoeba castellani
64
Primary amebic meningoencephalitis
Naegleria fowleri
65
Only ciliated protozoan to cause human dse - dysentery | Round based wide neck intestinal ulcers
Balantidium coli
66
Transmitted by ixodes tick
Babesia microti
67
Transmitted by sandfly | Infective promastigotes
Leishmania spp
68
Ttt for leishmaniasis
Na stibogluconate (antimony)
69
``` Shellfish poisoning Paralytic Neurotoxic Diarrhetic Amnesic ```
``` Shellfish poisoning Paralytic: saxitoxin Neurotoxic: brevetoxin Diarrhetic: okadaic Amnesic: domoic ```
70
Dx stage entamoeba
Trophozoites | Mature & immature cysts