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Flashcards in Protozoa Deck (70):
1

Produces cytopathic effect of E. Histolytica

Cysteine proteases

2

Mediates adherence of entamoeba

Lectin

3

Flask shaped colon ulcers
Dysentery without fever

Amebic colitis

4

Most common extraintestinal form of entamoeba
Anchovy sauce aspirate

Amebic liver abscess

5

Ttt for cyst carrier state of entamoeba

Diloxanide furoate

6

Luminal agents for entamoeba

Diloxanide furoate
Iodoquinol
Paromomycin

7

Falling leaf motility

Giardia lamblia

8

Variant surface protein

Giardia lamblia

9

Villous flattening, disruption of cytoskeleton Ultimately leads to enterocyte apoptosis

Giardia

10

Excessive flatus
Foul smelling diarrhea
Chronic: steatorrhea

Giardia

11

Acid fast parasite autoinfection in IS pts, self limited nonbloody diarrhea

Cryptosporidium parvum

12

Ttt for crytosporidium

Nitazoxanide

13

Infective and diagnostic stage of cryptosporidium

Thick walled oocysts

14

Pear shaped flagellated trophozoites

Trichimonas vaginalis

15

Greenish vaginal discharge

Trichomoniasis

16

Strawberry cervix
Ectocervicitis
Punctate hemorrhage

Trichomoniasis

17

Ttt for trichomoniasis

Metronidazole 2 g

18

Transmitted thru anopheles

Plasmodium

19

Infective stage of plasmodium

Sporozoites

20

Diagnostic stage of plasmodium

Trophozoites (ring forms)

21

Provides immunity to malaria

RBC defects

22

Banana shaped gametocyte

P. falciparum

23

Large round gametocyte

P. vivax

24

Recurrence of symptoms after temp abatement 2-4 weeks

Recrudescence
Falciparum, malariae

25

Return of disease after cessation, reactivation of hypnozoites (1-6 months)

Relapse
Vivax, ovale

26

Benign quartan

P. malariae

27

Malignant tertian

P. falciparum

28

Highest yield in blood samples for plasmodium

During fever or 2-3 hrs after peak

29

Punctate granulations in RBC

Schuffner - ovale, vivax

30

Coarse granulations in RBC

Maurer - falciparum

31

Fine granulations in RBC

Ziemann - malariae

32

Malarial or durck granulomas

Cerebral malaria

33

Intravascular hemolysis
Massive hemoglobinuria
ARF

Blackwater fever
P. falciparum

34

Septic shock due to plasmodium

Algid malaria

35

Endemic areas for plasmodium

Palawan
Kalinga apayao
Ifugao
Agusan del sur

36

Areas with Chloroquine resistant malaria

Palawan
Davao del norte
Compostela valley

37

Tissue schizonticide (liver) and gametocide (blood)

Primaquine

38

Blood schizonticide

Chloroquine
Quinine

39

Sporonticide in mosquito

Proguanil
Pyrimethamine

40

Ttt for Chloroquine resistant malariae

Mefloquine + doxycycline

41

Eradication of hypnozoites

Primaquine

42

Severe or pregnant

Chloroquine or quinine

43

Vivax and ovale ttt

Chloroquine + primaquine

44

Prophylaxis for plasmodium

Chloroquine

45

Prophylactic for areas with chloroquine resistance

Malarone
Mefloquine

46

Prophylaxis for MDR resistant falciparum

Doxycycline

47

Definitive host: domestic cat

Toxoplasma gondii

48

Preferred dx test for toxoplasmosis

IgM antibody

49

Intracranial calcifications

Congenital toxoplasmosis

50

Ttt for toxoplasmosis

Sulfadiazine + pyrimethamine

51

Transmitted by reduviid bug (triatoma)

Trypanosoma cruzi

52

Most often and severely affected tissue by t. Cruzi

Cardiac muscle

53

Periorbital edema in acute chagas dse

Romana's sign

54

Ttt of chagas dse

Nifurtimox

55

Dx stage of t. Cruzi and t. Bruceii

Trypomastigotes in blood

56

Transmission by tsetse fly (glossina) bite

Trypanosoma brucei

57

Remarkable antigenic variation
Cyclical fever spike every 2 weeks

Trypanosoma bruceii

58

Enlargement of post cervical LN

Winterbottom's sign
T. Bruceii

59

Hyperesthesia in t. Bruceii

Kerandel's sign

60

Plasma cells with cytoplasmic immunoglobulin globules

Mott cells in t. Bruceii encephalitis

61

Ttt for t. Bruceii

Suramin
Melarsoprol

62

Transmission by bivalve molluscs and fish from red tide

Dinoflagellates

63

Granulomatous amebic encephalitis

Acanthamoeba castellani

64

Primary amebic meningoencephalitis

Naegleria fowleri

65

Only ciliated protozoan to cause human dse - dysentery
Round based wide neck intestinal ulcers

Balantidium coli

66

Transmitted by ixodes tick

Babesia microti

67

Transmitted by sandfly
Infective promastigotes

Leishmania spp

68

Ttt for leishmaniasis

Na stibogluconate (antimony)

69

Shellfish poisoning
Paralytic
Neurotoxic
Diarrhetic
Amnesic

Shellfish poisoning
Paralytic: saxitoxin
Neurotoxic: brevetoxin
Diarrhetic: okadaic
Amnesic: domoic

70

Dx stage entamoeba

Trophozoites
Mature & immature cysts