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Psych Meds Flashcards

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1
Q

Ritalin

A

methylphenidate

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2
Q

Adderall

A

Dextroamphetamine

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3
Q

Ambien

A

Zolpidem

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4
Q

What is the mechanism of Ambien

A

Interacts with the GABA-Benzodiazepine receptor

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5
Q

Concerta

A

Methylphenidate

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6
Q

Vyvanse

A

Lisdexamfetamine

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7
Q

BuSpar

A

Buspirone

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8
Q

When is Buproprion Contraindicated

A

Patients with seizures`

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9
Q

Can BuSpar be used as an adjunct therapy for anxiety

A

You bet’ya

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10
Q

What other beneficial effects does buspar have in the treatment of anxiety and depression

A

Tends to have a stimulative effect which helps combat the neurovegetative state

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11
Q

Cymbalta

A

Duloxetine

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12
Q

Klonopin

A

Clonazepam

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13
Q

What is the half life of action of klonopin

A

20-50 hours

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14
Q

Remeron

A

Mirtazipine

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15
Q

What is the mechanism of Remeron

A

Antagonizes alpha-2 adrenergic and serotonin 5HT-2 receptors

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16
Q

Effexor

A

Venlafaxine

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17
Q

Pristiq

A

Desvenlafaxine

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18
Q

What is the mechanism of Desvenlafaxine

A

SNRI

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19
Q

What is desvenlafaxine used to treat

A

Major Depressive Disorder

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20
Q

Strattera

A

Atomoxetine

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21
Q

What is atomoxetine used to treat

A

ADHD

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22
Q

What is the mechanism of atomoxetine

A

Selectively inhibits Norepinephrine reuptake

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23
Q

Abilify

A

Aripiprazole

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24
Q

What is aripiprazole

A

2nd generation antipsychotic

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25
Ativan
Lorazepam
26
Aricept
Donepezil
27
What is the mechanism of Donepezil
Cholinesterase inhibitor
28
What is donepezil used to treat
Dementia
29
Namenda
Memantine
30
What is the mechanism of memantine
NMDA receptor Antagonist
31
Fioricept
Butabital / acetaminophen / caffeine
32
Flexeril
cyclobenzaprine
33
How is lithium used for depression?
As an adjunct to therapy. It will also help alleviate the compulsions.
34
What is the benefit of adding Abilify to pristiq
It improves the treatment of depression and helps control insomnia
35
Campral
Acamprosate
36
What is acamprosate used to treat
Alcohol dependence
37
What is the mechanism of acamprosate
effects the GABA receptors
38
Relpax
Eletriptan
39
What is eletriptan used to treat
Miagraine HA
40
What is the mechanism of Eletriptan
Activates the vascular 5HT-1 Receptors that cause vasoconstriction.
41
What is the mechanism of Viibryd
- SSRI | - Selectively inhibits serotonin reuptake and partially agonizes serotonin 5HT-1A receptors.
42
Amitiza
Lubiprostone
43
What is lubiprostone used to treat
Constipation predominant IBS
44
What is the mechanism of Lubiprostone?
activates ClC-2 chloride channels, increasing intestinal fluid secretion and motility (osmotic laxative)
45
What are the indications of a dopamine blockade
It will cause in an increase in prolactin leading to galactorhea, impotence, menstrual dysfunction and decreased libido
46
What is the side effect of thioridazine
causes retinal pigment deposits
47
What are the major side effects of clozapine
``` agranulocytosis orthostatic hypotension weight gain metabolic syndrome sedation constipation ```
48
What are the major side effects of chlorpromazine
jaundice and photosensitivity
49
What are the major side effects of Olanzapine
weight gain, sedation, hypotension dry mouth
50
What are the major side effects of Quitiapine
``` Sedation, orthostatic hypotension, akathisia, weight gain, dry mouth ```
51
What are the major side effects of Ziprasidone
Nausea weakness mild QT prolongation
52
What are the major side effects of aripiprazole
``` headache nausea akathisia tremor constipation` ```
53
What are the major side effects of Paliperidone
``` pakinsonism dystonia dyskinesia akathisia QT prolongation ```
54
Side effects of Topamax
Skinny and Stupid
55
What receptors are affected by antipsychotics
``` Also knows as neuroleptics block various receptors including: cholinergic adrenergic sertoninergic muscarinic histamine ```
56
What is the mechanism of action of the antipsychotics
blocking of dopamine receptors in the CNS, particular the D2 receptors in the mesocortical and mesolimbical systems of the brain
57
How does the potency of the antipsychotics differ
They differ in their affinity for the D2 receptor in the brain: Haloperidol - high affinity/potency Chlorpromazine - low affinity/potency
58
What is the onset of action for antipsychotics
may not become effective for several weeks to months. However, sedation and other side effects can occur rapidly
59
Can antipsychotics cure schizophrenia
Nope, but it can treat the symptoms
60
Name the phenothaizines
``` chlorpromazine (thorazine) Fluphenazine (prolixin) Trifluoperazine (stelazine) Thioridazine (Mellaril) Perphenazine (Trilafon) ```
61
What distinctive side effects does thioridazine cause
Pigmentary retinopathy. | May cause cardiac arrhythmias and conduction block
62
Name the Butyrophones
Haloperidol (Haldol) | Droperidol (Inapsine)
63
Other than psychotic states, what can haloperidol be used
Tourettes syndrome Huntingtons disease Phencyclidine overdoes
64
Name the classes of the traditional antipsychotics
Phenothiazines Butyrophenones Dibenzoxazepines Thioxanthenes
65
Name a drug that belongs to the dibenzoxazepines
loxapine (Loxitane)
66
Name a drug that belongs to the thioxanthenes
Thioxanthene (Navane)
67
What are the clinical applications of traditional antipsychotic agents
1. Treatment of any agitated or psychotic state (bipolar or schizophrenia) 2. Antiemetic therapy (phenothiazines except thioridazine) 3. Treatment of Tourettes syndrome (haloperidol) 4. Treatment of intractable hiccups (chlorpromazine) 5. Antipruritic therapy (promethazine)
68
How do the side effects vary with the different antipyschotics
The greater the affinity to the D2 receptor the greater the degree of side effect
69
What are the endocrine alterations associated with Antipsychotics
Galactorhea, amenorrhea, infertility, all likely due to blockade of dopamine release from the pituitary
70
What are the Anticholinergic effects associated with antipsychotics
Dry mouth constipation urinary retention blurry vision
71
What are the antiadrenergic effects associated with antipsychotics
light-headedness and orthostatic hypotension secondary to a-adrenergic blockade
72
What are the extrapyramidal side effects associated with antipsychotics
Akathisia (motor reslessness), parkinsonian syndrome (bradykinic rigidity) Neuroleptic malignant syndrome Tardive dyskinesia
73
Zyprexa
Olanzapine
74
What is olanzapine
2nd generation antipsychotic
75
Trileptal
Oxcarbazepine
76
What is the mechanism of Oxcarbazepine
Blocks voltage sensitive Na channels
77
What is oxcarbazepine indicated for
Seizures | Bipolar
78
Depakote
Divalproex sodium
79
What is divalproex sodium indicated to treat
Seizures Bipolar Migraine prophylaxis
80
What is the mechanism of Divalproex sodium
Increases GABA effects | May inhibit glutamate/NMDA receptor-mediated neuronal excitation
81
Geodon
ziprasidone
82
Invega
paliperidone

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