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Flashcards in Psych Meds Deck (82):
1

Ritalin

methylphenidate

2

Adderall

Dextroamphetamine

3

Ambien

Zolpidem

4

What is the mechanism of Ambien

Interacts with the GABA-Benzodiazepine receptor

5

Concerta

Methylphenidate

6

Vyvanse

Lisdexamfetamine

7

BuSpar

Buspirone

8

When is Buproprion Contraindicated

Patients with seizures`

9

Can BuSpar be used as an adjunct therapy for anxiety

You bet'ya

10

What other beneficial effects does buspar have in the treatment of anxiety and depression

Tends to have a stimulative effect which helps combat the neurovegetative state

11

Cymbalta

Duloxetine

12

Klonopin

Clonazepam

13

What is the half life of action of klonopin

20-50 hours

14

Remeron

Mirtazipine

15

What is the mechanism of Remeron

Antagonizes alpha-2 adrenergic and serotonin 5HT-2 receptors

16

Effexor

Venlafaxine

17

Pristiq

Desvenlafaxine

18

What is the mechanism of Desvenlafaxine

SNRI

19

What is desvenlafaxine used to treat

Major Depressive Disorder

20

Strattera

Atomoxetine

21

What is atomoxetine used to treat

ADHD

22

What is the mechanism of atomoxetine

Selectively inhibits Norepinephrine reuptake

23

Abilify

Aripiprazole

24

What is aripiprazole

2nd generation antipsychotic

25

Ativan

Lorazepam

26

Aricept

Donepezil

27

What is the mechanism of Donepezil

Cholinesterase inhibitor

28

What is donepezil used to treat

Dementia

29

Namenda

Memantine

30

What is the mechanism of memantine

NMDA receptor Antagonist

31

Fioricept

Butabital / acetaminophen / caffeine

32

Flexeril

cyclobenzaprine

33

How is lithium used for depression?

As an adjunct to therapy. It will also help alleviate the compulsions.

34

What is the benefit of adding Abilify to pristiq

It improves the treatment of depression and helps control insomnia

35

Campral

Acamprosate

36

What is acamprosate used to treat

Alcohol dependence

37

What is the mechanism of acamprosate

effects the GABA receptors

38

Relpax

Eletriptan

39

What is eletriptan used to treat

Miagraine HA

40

What is the mechanism of Eletriptan

Activates the vascular 5HT-1 Receptors that cause vasoconstriction.

41

What is the mechanism of Viibryd

- SSRI
- Selectively inhibits serotonin reuptake and partially agonizes serotonin 5HT-1A receptors.

42

Amitiza

Lubiprostone

43

What is lubiprostone used to treat

Constipation predominant IBS

44

What is the mechanism of Lubiprostone?

activates ClC-2 chloride channels, increasing intestinal fluid secretion and motility (osmotic laxative)

45

What are the indications of a dopamine blockade

It will cause in an increase in prolactin leading to galactorhea, impotence, menstrual dysfunction and decreased libido

46

What is the side effect of thioridazine

causes retinal pigment deposits

47

What are the major side effects of clozapine

agranulocytosis
orthostatic hypotension
weight gain
metabolic syndrome
sedation
constipation

48

What are the major side effects of chlorpromazine

jaundice and photosensitivity

49

What are the major side effects of Olanzapine

weight gain,
sedation,
hypotension
dry mouth

50

What are the major side effects of Quitiapine

Sedation,
orthostatic hypotension,
akathisia,
weight gain,
dry mouth

51

What are the major side effects of Ziprasidone

Nausea
weakness
mild QT prolongation

52

What are the major side effects of aripiprazole

headache
nausea
akathisia
tremor
constipation`

53

What are the major side effects of Paliperidone

pakinsonism
dystonia
dyskinesia
akathisia
QT prolongation

54

Side effects of Topamax

Skinny and Stupid

55

What receptors are affected by antipsychotics

Also knows as neuroleptics
block various receptors including:
cholinergic
adrenergic
sertoninergic
muscarinic
histamine

56

What is the mechanism of action of the antipsychotics

blocking of dopamine receptors in the CNS, particular the D2 receptors in the mesocortical and mesolimbical systems of the brain

57

How does the potency of the antipsychotics differ

They differ in their affinity for the D2 receptor in the brain:
Haloperidol - high affinity/potency
Chlorpromazine - low affinity/potency

58

What is the onset of action for antipsychotics

may not become effective for several weeks to months. However, sedation and other side effects can occur rapidly

59

Can antipsychotics cure schizophrenia

Nope, but it can treat the symptoms

60

Name the phenothaizines

chlorpromazine (thorazine)
Fluphenazine (prolixin)
Trifluoperazine (stelazine)
Thioridazine (Mellaril)
Perphenazine (Trilafon)

61

What distinctive side effects does thioridazine cause

Pigmentary retinopathy.
May cause cardiac arrhythmias and conduction block

62

Name the Butyrophones

Haloperidol (Haldol)
Droperidol (Inapsine)

63

Other than psychotic states, what can haloperidol be used

Tourettes syndrome
Huntingtons disease
Phencyclidine overdoes

64

Name the classes of the traditional antipsychotics

Phenothiazines
Butyrophenones
Dibenzoxazepines
Thioxanthenes

65

Name a drug that belongs to the dibenzoxazepines

loxapine (Loxitane)

66

Name a drug that belongs to the thioxanthenes

Thioxanthene (Navane)

67

What are the clinical applications of traditional antipsychotic agents

1. Treatment of any agitated or psychotic state (bipolar or schizophrenia)
2. Antiemetic therapy (phenothiazines except thioridazine)
3. Treatment of Tourettes syndrome (haloperidol)
4. Treatment of intractable hiccups (chlorpromazine)
5. Antipruritic therapy (promethazine)

68

How do the side effects vary with the different antipyschotics

The greater the affinity to the D2 receptor the greater the degree of side effect

69

What are the endocrine alterations associated with Antipsychotics

Galactorhea,
amenorrhea,
infertility,
all likely due to blockade of dopamine release from the pituitary

70

What are the Anticholinergic effects associated with antipsychotics

Dry mouth
constipation
urinary retention
blurry vision

71

What are the antiadrenergic effects associated with antipsychotics

light-headedness and orthostatic hypotension secondary to a-adrenergic blockade

72

What are the extrapyramidal side effects associated with antipsychotics

Akathisia (motor reslessness),
parkinsonian syndrome (bradykinic rigidity)
Neuroleptic malignant syndrome
Tardive dyskinesia

73

Zyprexa

Olanzapine

74

What is olanzapine

2nd generation antipsychotic

75

Trileptal

Oxcarbazepine

76

What is the mechanism of Oxcarbazepine

Blocks voltage sensitive Na channels

77

What is oxcarbazepine indicated for

Seizures
Bipolar

78

Depakote

Divalproex sodium

79

What is divalproex sodium indicated to treat

Seizures
Bipolar
Migraine prophylaxis

80

What is the mechanism of Divalproex sodium

Increases GABA effects
May inhibit glutamate/NMDA receptor-mediated neuronal excitation

81

Geodon

ziprasidone

82

Invega

paliperidone