Psychosis And Schizophrenia Flashcards
(17 cards)
What are positive symptoms of schizo?
Delusions
Hallucinations
Disorganisation
What are negative symptoms of schizo?
Social withdrawal
Neglect
Poor hygiene
What is the cause of schizo?
Mechanism to treat?
Elevated dopamine levels so to treat we eant to DECREASE
What are the 2nd gen antipsychotics (6)
Amisulpride
Aripiprazole
Clozapine
Risperidone
Olanzapine
Quetiapine
Which antipaychotics cause postural hypotension
Aripiprazole
Risperidone
Clozapine
Quetiapine
Which antipaychotic vauses hypertension
Clozapine
Which antipsychotic causes stroke
Risperidone
Olanzapine
Which cause qt prolongation and sedation
All
Which antipaychotics cause epses
1st gen
Which antipsychotics cause hyperglycaemia
Risperidone
Olanzapine
Quetiapine
Clozapine
Which antipsychotics cause weight gain
Olanzapine
Clozapine
Which antipaychotics do not cause hyperprolactinaemia
Clozapine
Olanzapine
Quetiapine
Aripiprazole
What interactions to be aware of for antipsychotics
Sedatives
Hypotensives
QT prolongations
CYP enzyme inducer and inhibitors
When is clozapine prescribed
When 2+ antipsychotics inculding 1 2nd gen has been used for adequate time
MHRA clozapine when to monitor levels
Changes in smoking
Pneumonia or serious infection
Risks/signs of toxicity
What are 3 crucial clozapine side effects
Agranulocytosis/thrombocytopenia
Myocarditis/pericarditis/pericardial effusion/cardiomyopathy
Intestinal peristalsis impairment
What is the guidance around clozapine in pregnancy and breastfeeding
Avoid in bf
Caution in pregnancy
