Substance Dependence Flashcards

(17 cards)

1
Q

What is 1st line treatment for moderate severe alcohol use dependence

A

Psychological CBT
Acamproste or naltrexone

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2
Q

What is 2nd line for moderate severe alcohol use disorders

A

Disulfiram

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3
Q

What to give in Wernickes Encephalopathy

A

Thiamine vitamin B1

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4
Q

What to give for withdrawal symptoms in alcohol use patients

A

Chlordiazepoxide
Diazepam

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5
Q

What to give for withdrawal seizures in alcohol misuse

A

Lorazepam

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6
Q

What to give 1st and 2nd for delirium in alcohol misuse

A

Lorazepam
Haloperidol

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7
Q

What are the long acting NRT options and for who

A

16hrs for nightmares and pregnancy

24hrs for wake with cravings

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8
Q

What are short acting nrt examples

A

Gum
Inhalator
Lozenges
Nasal spray
Oral spray
Sublingual tablets

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9
Q

What are 2 medications that can be given in nicotine dependence

A

Varenicline
Bupropion

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10
Q

What is the MHRA warning for bupropion

A

Serotonin syndrome risk

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11
Q

What are the cautions of Varenicline

A

CVD
psychiatric illness
Epilepsy
Renal impairment

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12
Q

Wha is 1st line for opioid detoxification

A

Methadone
Buprenorphine

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13
Q

What are withdrawal symptoms of opioids

A

D+V, stomach cramps, agitation, headaches, insomnia

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14
Q

Why is buprenorphine chosen over methadone

A

Lower risk of fatal overdose
Can be given with naloxone - discourages injecting
Less mental clouding and sedation effect
MR suitable for adherence issues

Methadone can cause QT prolongation

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15
Q

Why is methadone chosen over buprenorphine

A

More effective in retaining patients on treatment

More suitable for patients using large amounts of heroin

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16
Q

What is the expected period of time that patients need daily supervised consumption

A

First 3 months

17
Q

What to do in a missed dose and when to refer back to prescriber

A

Missed doses are not replaced

If miss 3+ days refer back to prescriber