Flashcards in PUD Drugs Deck (58)
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1
H. pylori Triple combination Tx
Omeprazole
Amoxicillin
Clarithromycin
2
Triple combo Tx MOA
Reduce gastric pH; Abx action of H. pylori
3
Triple combo Tx indication
H. pylori associated ulcers
4
H. pylori Quadruple combination Tx
Omeprazole
Metronidazole
Tetracycline
Bismuth
5
Ranitidine class
H2RB
6
Ranitidine MOA
Competitively inhibits H2Rs in gastric parietal cells reducing basal and stimulated acid secretion
7
Ranitidine indication
PUD, GERD
8
Ranitidine side effect
Possible B12 deficiency with long term use
9
When should you take Ranitidine?
~1900h
10
Omeprazole class
PPI
11
Omeprazole MOA
Reduces basal and stimulated gastric parietal cell proton pump acid secretion
12
Omeprazoel indication
PUD, GERD, NSAID ulcer Px, Stress ulcer Px in critically ill
13
Omeprazole side efect
May cause gastric atrophy/B12 deficiency in long term use
14
Omeprazole Dx-Dx
May decrease absorption of Fe, Zn, Ca++
15
Pantoprazole class
PPI
16
Pantoprazole has the least effect on this med, compared to other PPIs...
Clopidrogrel
17
Sucralfate class
Mucosal surfactant
18
Sucralfate MOA
Forms a paste and selectively binds to ulcers and erosions; stimulates mucus, bicarb, and prostaglandin secretion
19
Sucralfate indication
Duodenal and gastric ulcers
20
Sucralfate side effect
Constipation
21
After taking Sucralfate, how long do you have to wait to take nay other meds?
2 hours
22
What element does Sucralfate contain?
Al
23
Who needs to avoid the Al?
Renal failure Pts
24
Dicyclomine class
Muscarinic antagonist
25
Dicyclomine MOA
M receptor anticholinergic drug
26
Dicyclomine indication
IBS cramps
27
Dicyclomine side effect
Dry mouth
28
Dicyclomine contraindication
Glaucoma
29
Alternagel class
Antacid
30
Alternagel MOA
Neutralizes HCl to AlCl3 and H2O
31
Alternagel indication
Hyperacidity
32
Alternagel side effect
hypophosphatemia
33
Alternalgel contraindication
Al allergy
34
Alternalgel Dx-Dx
Binds to and inhibits absorption of many drugs
35
MOM class
Antacid
36
MOM MOA
Reacts with HCl to form MgCl; osmotic absorption of fluids distends colon and increases peristalsis
37
MOM indication
Dyspepsia, constipation
38
MOM side effect
Diarrhea
39
MOM Dx-Dx
Binds to and inhibits absorption of many drugs
40
Cytotec class
NSAID protectant
41
Cytotec MOA
Replaced prostaglandins
42
Cytotec indication
NSAID associated ulcers, Pts taking NSAIDs at high risk of gastric bleeding
43
Cytotec pregnancy class
X - abortifactant
44
Saxenda class
GLP-1 Receptor Agonist; Wt loss drug
45
Saxenda MOA
Increases insulin secretion
Decreases glucagon secretion
Decreases gastric emptying and food intake
46
Saxenda indication
T2DM adjunct therapy, Wt loss
47
Saxenda side effect
hypoglycemia
48
Saxenda pregancy class
X
49
D/C Saxenda if you haven't lost at least _____ of your body wt in ______.
4%
16 weeks
50
Orlistat class
Lipase inhibitor; Wt loss drug
51
Orlistat MOA
Reversibly inhibits lipase secretion, reducing fat absorption by ~30%
52
Orlistat indication
Obesity management in Pts with a BMI >30 or >27 with risk factors
53
Orlistat side effect
Oily rectal discharge
54
I'm sorry, I'm sorry, what did you say could happen on Orlistat?
I said oily rectal discharge
55
I would rather wreck myself at the gym
But we all make choices
56
Orlistat pregnacny class
X
57
D/C Orlistat in _____ if you haven;t lost at least _____ of your body wt.
12 weeks
5%
58
