PUD Drugs Flashcards Preview

GI Pharm > PUD Drugs > Flashcards

Flashcards in PUD Drugs Deck (58)
Loading flashcards...
1

H. pylori Triple combination Tx

Omeprazole
Amoxicillin
Clarithromycin


2

Triple combo Tx MOA

Reduce gastric pH; Abx action of H. pylori

3

Triple combo Tx indication

H. pylori associated ulcers

4

H. pylori Quadruple combination Tx

Omeprazole
Metronidazole
Tetracycline
Bismuth

5

Ranitidine class

H2RB

6

Ranitidine MOA

Competitively inhibits H2Rs in gastric parietal cells reducing basal and stimulated acid secretion

7

Ranitidine indication

PUD, GERD

8

Ranitidine side effect

Possible B12 deficiency with long term use

9

When should you take Ranitidine?

~1900h

10

Omeprazole class

PPI

11

Omeprazole MOA

Reduces basal and stimulated gastric parietal cell proton pump acid secretion

12

Omeprazoel indication

PUD, GERD, NSAID ulcer Px, Stress ulcer Px in critically ill

13

Omeprazole side efect

May cause gastric atrophy/B12 deficiency in long term use

14

Omeprazole Dx-Dx

May decrease absorption of Fe, Zn, Ca++

15

Pantoprazole class

PPI

16

Pantoprazole has the least effect on this med, compared to other PPIs...

Clopidrogrel

17

Sucralfate class

Mucosal surfactant

18

Sucralfate MOA

Forms a paste and selectively binds to ulcers and erosions; stimulates mucus, bicarb, and prostaglandin secretion

19

Sucralfate indication

Duodenal and gastric ulcers

20

Sucralfate side effect

Constipation

21

After taking Sucralfate, how long do you have to wait to take nay other meds?

2 hours

22

What element does Sucralfate contain?

Al

23

Who needs to avoid the Al?

Renal failure Pts

24

Dicyclomine class

Muscarinic antagonist

25

Dicyclomine MOA

M receptor anticholinergic drug

26

Dicyclomine indication

IBS cramps

27

Dicyclomine side effect

Dry mouth

28

Dicyclomine contraindication

Glaucoma

29

Alternagel class

Antacid

30

Alternagel MOA

Neutralizes HCl to AlCl3 and H2O

31

Alternagel indication

Hyperacidity

32

Alternagel side effect

hypophosphatemia

33

Alternalgel contraindication

Al allergy

34

Alternalgel Dx-Dx

Binds to and inhibits absorption of many drugs

35

MOM class

Antacid

36

MOM MOA

Reacts with HCl to form MgCl; osmotic absorption of fluids distends colon and increases peristalsis

37

MOM indication

Dyspepsia, constipation

38

MOM side effect

Diarrhea

39

MOM Dx-Dx

Binds to and inhibits absorption of many drugs

40

Cytotec class

NSAID protectant

41

Cytotec MOA

Replaced prostaglandins

42

Cytotec indication

NSAID associated ulcers, Pts taking NSAIDs at high risk of gastric bleeding

43

Cytotec pregnancy class

X - abortifactant

44

Saxenda class

GLP-1 Receptor Agonist; Wt loss drug

45

Saxenda MOA

Increases insulin secretion
Decreases glucagon secretion
Decreases gastric emptying and food intake

46

Saxenda indication

T2DM adjunct therapy, Wt loss

47

Saxenda side effect

hypoglycemia

48

Saxenda pregancy class

X

49

D/C Saxenda if you haven't lost at least _____ of your body wt in ______.

4%
16 weeks

50

Orlistat class

Lipase inhibitor; Wt loss drug

51

Orlistat MOA

Reversibly inhibits lipase secretion, reducing fat absorption by ~30%

52

Orlistat indication

Obesity management in Pts with a BMI >30 or >27 with risk factors

53

Orlistat side effect

Oily rectal discharge

54

I'm sorry, I'm sorry, what did you say could happen on Orlistat?

I said oily rectal discharge

55

I would rather wreck myself at the gym

But we all make choices

56

Orlistat pregnacny class

X

57

D/C Orlistat in _____ if you haven;t lost at least _____ of your body wt.

12 weeks
5%

58

All that oily rectal discharge, and I didn't even loose 5%.

Ain't that a kick in the oily pants