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Flashcards in Pancreatic Drugs Deck (47)
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1

Viokase: class

Pancreatinc enzymes

2

Viokase: class

Pancreatinc enzymes

3

Viokase: MOA

Supplemental lipase, amylase, protease

4

Viokase: indication:

Chronic pancreatitis

5

Viokase: contraindication

Acute or exacerbation of chronic pancreatitis

6

What does dairy do to Viokase?

Decreases efficacy

7

Demerol: class

Analgesic

8

Demerol: MOA

Binds to mu receptors in CNS and inhibits ascending pain pathways

9

Demerol: indications

Short term peri-op and acute pacreatitis

10

Demerol: side effects

CNS depression, HOTN, seizures from toxic metabolite

11

Demerol: Contraindication

Renal disease, elderly, recent MAOI use

12

How long should you limit the use of Demerol to?

13

Octreotide: class

Somatostatin analogue

14

Octreotide: MOA

Inhibits bowel secretions
Dose related effect on motility
Splanchnic arteriole contraction

15

Octreotide: indication

Diarrhea secondary to bowel dysmotility, carcinois,
VIP-oma, vagotomy, dumping syndrome, short bowel syndrome, HIV diarrhea, GI bleed

16

Octreotide: Side efects

Steatorrhea, Gallstones (>50% in long term use)

17

Octreotide: contraindication

Bowel obstruction

18

Octreotide: Dx-Dx

insulin, PO hypoglycemics, BBs, CCBs

19

Ranitidine: class

H2RB

20

Ranitidine: MOA

Competitively inhibits H2Rs in gastric parietal cell reducing basal and stimulated acid production

21

Ranitidine: indications

PUD, GERD

22

Ranitidine: side effect

Possible B12 deficiency in long term use

23

Omeprazole: class

PPI

24

Omeprazole: MOA

Reduces basal and stimulated parietal cell proton pump acid secretion

25

Omeprazole: indications

PUD, GERD, NASID ulcer Px, stres ulcer Px in critically ill

26

Omeprazole: side effects

Possible gastric atrophy and/or B12 deficiency in long term use

27

Omeprazole: Dx-Dx

May decrease Fe/Zn/Ca++ absorption

28

Pantoprazole: class

PPI

29

What drug does Pantoprazole have little effect on, compared to Omeprazole?

Clopidogrel

30

What time is gastric acid at it's highest?

1900h

31

When should you take H2RBs and PPIs?

1800h

32

Primaxin: class

Abx

33

Primaxin: MOA

Lyses bacterial cells

34

Primaxin: indication

Intra abd infection, liver abscess

35

Primaxin: contraindication

Sensitivity to IM Lidocaine

36

Cipro: class

FQ Abx

37

Cipro: MOA

Inhibits DNA gyrase

38

Cipro: indication

Mild diverticulitis
Traveler's diarrhea

39

Cipro: contraindications

Age

40

Metronidazole: class

Abx

41

Metronidazole: MOA

Inhibits bacterial protein synthesis

42

Metronidazole: indication

Diverticulitis, C. diff

43

Metronidazole pregnancy category

B

44

Vancomycin: class

Abx

45

Vancomycin: MOA

Inhibits glycopeptide polymeration, inhibiting bact cell wall synthesis

46

Vancomycin: indication

Staph enetrocolitis, C. diff

47

Vancomycin: side effects

PO: bitter taste
IV: nephro/neuro/ototoxicity, Red Man Syndrome