Flashcards in Pancreatic Drugs Deck (47)
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1
Viokase: class
Pancreatinc enzymes
2
Viokase: class
Pancreatinc enzymes
3
Viokase: MOA
Supplemental lipase, amylase, protease
4
Viokase: indication:
Chronic pancreatitis
5
Viokase: contraindication
Acute or exacerbation of chronic pancreatitis
6
What does dairy do to Viokase?
Decreases efficacy
7
Demerol: class
Analgesic
8
Demerol: MOA
Binds to mu receptors in CNS and inhibits ascending pain pathways
9
Demerol: indications
Short term peri-op and acute pacreatitis
10
Demerol: side effects
CNS depression, HOTN, seizures from toxic metabolite
11
Demerol: Contraindication
Renal disease, elderly, recent MAOI use
12
How long should you limit the use of Demerol to?
13
Octreotide: class
Somatostatin analogue
14
Octreotide: MOA
Inhibits bowel secretions
Dose related effect on motility
Splanchnic arteriole contraction
15
Octreotide: indication
Diarrhea secondary to bowel dysmotility, carcinois,
VIP-oma, vagotomy, dumping syndrome, short bowel syndrome, HIV diarrhea, GI bleed
16
Octreotide: Side efects
Steatorrhea, Gallstones (>50% in long term use)
17
Octreotide: contraindication
Bowel obstruction
18
Octreotide: Dx-Dx
insulin, PO hypoglycemics, BBs, CCBs
19
Ranitidine: class
H2RB
20
Ranitidine: MOA
Competitively inhibits H2Rs in gastric parietal cell reducing basal and stimulated acid production
21
Ranitidine: indications
PUD, GERD
22
Ranitidine: side effect
Possible B12 deficiency in long term use
23
Omeprazole: class
PPI
24
Omeprazole: MOA
Reduces basal and stimulated parietal cell proton pump acid secretion
25
Omeprazole: indications
PUD, GERD, NASID ulcer Px, stres ulcer Px in critically ill
26
Omeprazole: side effects
Possible gastric atrophy and/or B12 deficiency in long term use
27
Omeprazole: Dx-Dx
May decrease Fe/Zn/Ca++ absorption
28
Pantoprazole: class
PPI
29
What drug does Pantoprazole have little effect on, compared to Omeprazole?
Clopidogrel
30
What time is gastric acid at it's highest?
1900h
31
When should you take H2RBs and PPIs?
1800h
32
Primaxin: class
Abx
33
Primaxin: MOA
Lyses bacterial cells
34
Primaxin: indication
Intra abd infection, liver abscess
35
Primaxin: contraindication
Sensitivity to IM Lidocaine
36
Cipro: class
FQ Abx
37
Cipro: MOA
Inhibits DNA gyrase
38
Cipro: indication
Mild diverticulitis
Traveler's diarrhea
39
Cipro: contraindications
Age
40
Metronidazole: class
Abx
41
Metronidazole: MOA
Inhibits bacterial protein synthesis
42
Metronidazole: indication
Diverticulitis, C. diff
43
Metronidazole pregnancy category
B
44
Vancomycin: class
Abx
45
Vancomycin: MOA
Inhibits glycopeptide polymeration, inhibiting bact cell wall synthesis
46
Vancomycin: indication
Staph enetrocolitis, C. diff
47
