Pulmonary Histology Week 1 Flashcards Preview

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Flashcards in Pulmonary Histology Week 1 Deck (129)
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1

German physician _________ first describes and named the ________ and was published in lung diseases and angina pectoris

Hans Kohn, Pore of Kohn

2

The respiratory stem is a combination of _______, _________, _______, and _______

cartilage, elastic fibers, collagen fibers, smooth muscle fibers

3

The concentration of ______ in the respiratory system is inversely proportional to the _____

elastic fiber, diameter

4

Elastic fibers found in lamina propria of the respiratory system run _______

longitudinally

5

The _____ of the respiratory system is mostly circular

smooth muscle

6

The _________ of the respiratory system provides conduit to transfer air

conducting portion

7

How does the conducting portion condition the air?

cleans, moistens, and warms air

8

What are the six cell types in the generic respiratory epithelium?

1) ciliated columnar cells, columnar cells, 2) mucous goblet cells, 3) brush cells, 4) diffuse endocrine or small granule cells, 5) basal cells or immature cells

9

The ______ produce serous secretion

columnar cells

10

The ______ have no cilia yet many microvilli. There are two kinds.

Brush cells

11

Describe the two types of brush cells.

One kind acts like goblet cells releasing mucinogen. Other kind has nerve ending on basal surface.

12

Name the two proposed functions of the nerve endings on the basal surface of some brush cells

sensory receptor for gas volume and o2/co2 conentration; intraepithelial receptor for trigeminal N/sneeze reflex

13

The mucous goblet cells continue until the _________. Describe the two functions.

terminal bronchiole. 1) synthesize mucinogen which when hydrated turns into mucous; 2) trap and remove bacteria/particles; 3)

14

The _________ are the most common types of cells and continue until the respiratory portion.

Ciliated columnar cells

15

In what direction do the cilia of ciliated columnar cells beat?

towards the mouth

16

The ________ are thought to control mucous and seromucous secretion and possibly vessel diameter

Diffuse endocrine or small granule cells

17

The __________ rest on the basement membrane and do not reach lumen and are therefore "psuedostratified." They appear to be stem cells.

Basal cells or immature cells

18

_________ is the abnormal transformation of a tissue to a form which is not normal in response to a disease process, a physical or chemical event

Metaplasia

19

Describe metaplasia in smoker's lungs

Increase in goblet cells in resp epithelium due to pollutants and decrease in cilia due to carbon monoxide

20

In the nasal cavity, the air is filtered, warmed and humidified by the ______

nasal mucosa

21

The ______ is the anterior portion of the nasal cavity

vestibule

22

The nasal fossa contains _____, ______, and _____ conchae AKA _____

inferior, middle, and superior; turbinates

23

The nasal cavity also contains vibrissae and ______ and ______ mucosa

olfactory, respiratory

24

In the lamina propria of the nasal cavity, ______ release IgA and IgE. Describe the action of IgE.

plasma cells. IgE binds to receptors on mast cells and basophils --> inflammatory mediators released

25

Drainage from maxillary sinus infections can be seen below the _________

middle concha

26

Why is the nasal cavity a great site for drug delivery?

There is convenient access to a superficial venous plexus beneath the nasal cavity mucosa

27

_______ are venous plexi located in the lamina propria that enlarge alternately on two sides of nasal cavity.

Swell bodies

28

How often do swell bodies enlarge and why?

about every 30 minutes. The mucosa on occluded side has time to recover from desiccation and help to direct air to olfactory epithelium.

29

The olfactory epithelium is located on the roof of the _______ and on the superior ______

nasal cavity, superior nasal conchae

30

What are the four cell types in the olfactory epithelium?

olfactory cell, substentacular cell, basal cell, and brush cells