Q3 Exam 2 Flashcards
(93 cards)
lobes of the liver
left (lateral and medial), quadrate, right (medial and lateral), caudate (papillary and caudate process)
how much of the liver can you remove?
70%
when is U/S vs CT useful in liver diagnostics
US: focal or multifocal hepatic disease
CT: vascular anomalies and surgical planning
punch biopsy depth in liver
no more than 50% thickness of lobe
most common primary liver tumors in dogs vs cats
hepatocellular carcinoma, massive, left lobe
bile duct tumors (often more benign)
most common metastases in the liver
lymphosarcoma, carcinomas, sarcomas (like HGS)
why is the left lobes easiest to resect
pedunculated, no association with gall bladder or CVC
ideal hepatic surgical candidate
left, one lobe, less than 50% of liver mass, not diffuse or nodular
hepatic cysts
usually incidental, only treat if large enough to interfere with other organs, r/out abscess
cats extrahepatic biliary anatomy
common bile duct and pancreatic duct JOIN before entering duodenum
common biochemistry changes with hepatobiliary disease in dogs vs cats
dogs- cholestatic (ALP,GGT)
cats- any elevation in one of the 4 liver enzymes worrying
when to treat biliary sludge
secondary disease, more than grade 3, biliary sludge not gravity dependent, or at risk for a mucocele
most likely cause of gallbladder issues
hypomotility and hydrophobic bile acid overproduction
gallbladder mucocele in cats
not a thing
medical therapy for mild signs of gallbladder mucocele
ursodiol, SAMe, antibiotics, supportive care, low fat diet, search for endocrinopathy
cholecystitis dx
histo gold standard, usually assumptive on U/S and clinical signs, can do bile culture too!
cholecystitis tx
medical therapy for mild cases, still likely hospitalize (antibiotics, ursodiol, hepatoprotectants, low fat diet), medical and surgery for mod to severe cases
neutrophilic cholangitis
leading cause ascending bacterial infection (E coli, enterococcus, clostridium), will see fever often! make sure to feed cats!!! penicillin vs penicillin and fluoroquinolone
lymphocytic cholangitis
cats with episodic signs, immune mediated, liver biopsies (weird), need immune suppression and hepatoprotectants
hepatic lipidosis biochemical changes
increased ALP, hyperbilirubinemia, take to U/S!
ALT
hepatocellular injury
most sensitive hepatic function test
bile acids (not necessary if jaundiced), detects CH only 50%
breeds predisposed to chronic hepatitis
cocker spaniels, dobermans, dalmations, westies
infectious diseases causing hepatitis
lepto, leishmaniasis, histoplasmosis, protozoal