Quick Facts Flashcards
(39 cards)
Drugs not cleared with dialysis
Propranolol
Nicardepine
Vancomyacin
Verapamil
Drugs contraindicated in a B12 deficiency
Nitroprusside
Nitrous Oxide
Tx of Migrainse HA prophalaxis
Propranolol
Timolol
Drugs that cause Shivering
Thiopental
CYP Inhibitors
Cimetidine prolongs diazepam
Erythromycin prolongs diazepam
Drugs that potentiate NMBs
Beta Blockers
Calcium Channel Blockers (verapamil, nicardapine, diltiazem)
Furosemide
Drugs that inhibit acetylcholinesterase
Esmolol
Drugs to treat increased ICP
Furosemide: decrease CSF production by block Na transport in glial tissue
Mannitol: osmotic diuretic
Drugs not given to MG
Glycopyrolate
Scopolamine
Tetracaine
Chloroprocaine
Drugs contraindicated with phosphodiasterase/PDE-5 Inhibitors
Nitroglycerine NTG paste Prazosin (minipress) Phenozybenzamine Phentolamine Clonidine
Drugs that inhibit Phosphodiesterase
Amrinone
Milrinone
Aminophilline
*lead to increased intracellular cAMP and/or cGMP and result in positive inotropic effect and vasodilation
drugs that potentiate cardiac glycosides: DIGOXIN
Esmolol (enhances digoxin effects)
Calcium Gluconate/Chloride (contraindicated with suspected/known dig toxicity)
Adenosine (prolongs phase 4 cardiac same as digoxin)
Ancef (increase dig and r/f toxicity)
Azythromycin increases dig levels
Drugs that treat SVT
Phynelephrine Methozamine (alpha agonist similar to phynelephrine) Edrophonium Esmolol Propranolol Verapamil Diltiazem Adenosine Digoxin (last choice)
Drugs that prolong QT interval
Droperidol (increase QT) Promethazine (QT changes) Ondensetron (prolongs QT) Sevoflurane Isoflurane
Drugs that can lead to Pulmonary Edema
Naloxone Phenylephrine Isopreterenol Terbutaline Propranolol (with cocaine toxicity)
Drugs that may lead to myocardial ischemia
Norepinephrine Isopreterenol Dobutamine Ephedrive All of these have Beta 1 effects that will stress the heart
Do not give to patients with IHSS (idiopathic hypertrophic sub aortic stenosis)
Dobutamine Digoxin Nicardipine Milrinone (caution) no spinal or epidural blockes all of these will really drop BP
Give these drugs with IHSS
Beta Blockers: Counteract sympathetic activation and ecrease obstruction
Calcium Chennel Blockers
Phenylephrine: OK because it is pure alpha adrenergic agonist and doesn’t augment HT but it does increase SVR. Second choice behind pure maintenance of volume status
Do NOT give to 2nd and 3rd degree heart blocks
Atropine (with Mobitz II) Adenosine Esmolol Labetelol Propranol Digoxin most B-blockers Verapamil Nicardipine
Tx of Prophylactic endocarditis
Moderate risk
Ampicilline IV 2 g 30 min before procedure (Allergic to PNC- give 1- Clindomycin 600 mg or 2- Cefazoline 1 g or 3- Vancomycine 1 g
Tx of Prophylactic endocarditis
High risk
Ampicillin IV 2 g 30 minutes and Getamycine 1.5 mg/kg
Allergic to PNC?
give 1. 1 g Vancomycine and Gent. 1.5 mg/kg
Nipride and Cyaide toxicity
cyanide levels > 2 mcg/dl
thiocyanate level 35-100 mcg/ml
s/s of central anticholinergic syndrome
unconsciousness hallucination agitation delirium dry mouth tackycardia atropine flushing atropine fever impaired vision
what causes central anticholinergic syndrome?
increased ACh availability at muscarinic receptors
