Quinolones Flashcards

0
Q

What is the mechanism of action for quinolone a?

A

Disrupt the bacterial DNA molecules

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1
Q

What is the newest antibiotic that is only used on serious infections?

A

Quinolones

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2
Q

How are quinolones absorbed best?

A

Oral or parenteral administration

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3
Q

How are quinolones absorbed in mature ruminants orally?

A

Poor

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4
Q

What happens to quinolones in the presence of food?

A

Absorbed slowly

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5
Q

How are quinolones distributed?

A

Penetrate most tissues and at high concentrations except CNS

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6
Q

How are quinolones bio transfused?

A

Metabolized by liver

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7
Q

How are quinolones excreted?

A

Bile into intestinal tract and excreted by kidneys

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8
Q

What do quinolones effect?

A

G-

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9
Q

What animals can suffer articulate cartilage damage from quinolones?

A

Growing dogs, horses < 3, and pregnant animals

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10
Q

Besides articular damage what else can quinolones cause?

A

Crystal formation in urine

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