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Pharmacology II > Quiz 2 > Flashcards

Quiz 2 Flashcards

(59 cards)

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1
Q

Phenelzine

A

Monoamine oxidase inhibitors (MAOI)

Inhibit metabolism of NE, serotonin, and dopamine

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2
Q

Amitriptyline

A 
Tricyclic antidepressant (TCA)
Block reuptake of NE and serotonin (inhibit transporter protein)
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3
Q

Citalopram

A

Selective serotonin reuptake inhibitor (SSRI)

Block reuptake of serotonin (highly selective)

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4
Q

Duloxetine

A

Serotonin/Norepinephrine reuptake inhibitor (SNRI)

Block reuptake of NE and serotonin (non-selective)

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5
Q

Bupropion

A

Atypical antidepressant

Weak dopamine and NE reuptake inhibitor

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6
Q

Clomipramine

A 
Tricyclic antidepressant (TCA)
Block reuptake of NE and serotonin (inhibit transporter protein)
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7
Q

Desipramine

A 
Tricyclic antidepressant (TCA)
Block reuptake of NE and serotonin (inhibit transporter protein)
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8
Q

Escitalopram

A

Selective serotonin reuptake inhibitor (SSRI)

Block reuptake of serotonin (highly selective)

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9
Q

Selegiline

A

Monoamine oxidase inhibitor (MAOI)

Inhibit metabolism of NE, serotonin, and dopamine

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10
Q

Venlafaxine

A

Serotonin/Norepinephrine reuptake inhibitor (SNRI)

Block reuptake of NE and serotonin (non-selective)

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11
Q

Fluoxetine

A

Selective serotonin reuptake inhibitor (SSRI)

Block reuptake of serotonin (highly selective)

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12
Q

Mirtazapine

A

Atypical antidepressant

Enhances serotonin and NE neurotransmission (blocks presynaptic a2 receptors)

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13
Q

Tranylcypromine

A

Monoamine oxidase inhibitor (MAOI)

Inhibit metabolism of NE, serotonin, and dopamine

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14
Q

Doxepin

A 
Tricyclic antidepressant (TCA)
Block reuptake of NE and serotonin (inhibit transporter protein)
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15
Q

Imipramine

A 
Tricyclic antidepressant (TCA)
Block reuptake of NE and serotonin (inhibit transporter protein)
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16
Q

Nefazodone

A

Atypical antidepressant

Weak inhibitor of serotonin reuptake

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17
Q

Trazodone

A

Atyipcal antidepressant

Weak inhibitor of serotonin reuptake

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18
Q

Nortriptyline

A 
Tricyclic antidepressant (TCA)
Block reuptake of NE and serotonin (inhibit transporter protein)
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19
Q

Protriptyline

A 
Tricyclic antidepressant (TCA)
Block reuptake of NE and serotonin (inhibit transporter protein)
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20
Q

Paroxetine

A

Selective serotonin reuptake inhibitor (SSRI)

Block reuptake of serotonin (highly selective)

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21
Q

Sertraline

A

Selective serotonin reuptake inhibitor (SSRI)

Block reuptake of serotonin (highly selective)

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22
Q

Alprazolam

A

Benzodiazepine
Bind to benzodiazepine receptor; increase the affinity of GABA for its receptor
Enhances inhibitory effect of GABA
Decrease release of GABA

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23
Q

Flumazenil

A

Benzodiazepine antagonist

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24
Q

Buspirone

Study These Flashcards
A

Serotonin receptor agonist

25
Chlordiazepoxide
Benzodiazepine Bind to benzodiazepine receptor; increase the affinity of GABA for its receptor Enhances inhibitory effect of GABA Decrease release of GABA
26
Pentobarbital
Bind to barbiturate receptor; increase the affinity of GABA for its receptor Enhances inhibitory effect of GABA
27
Clorazepate
Benzodiazepine Bind to benzodiazepine receptor; increase the affinity of GABA for its receptor Enhances inhibitory effect of GABA Decrease release of GABA
28
Phenobarbital
Bind to barbiturate receptor; increase the affinity of GABA for its receptor Enhances inhibitory effect of GABA
29
Eszopiclone
BZD like drug Bind to benzodiazepine receptor; increase the affinity of GABA for its receptor Enhances inhibitory effect of GABA
30
Clonazepam
Benzodiazepine Bind to benzodiazepine receptor; increase the affinity of GABA for its receptor Enhances inhibitory effect of GABA Decrease release of GABA
31
Diazepam
Benzodiazepine Bind to benzodiazepine receptor; increase the affinity of GABA for its receptor Enhances inhibitory effect of GABA Decrease release of GABA
32
Secobarbital
Barbituate Bind to barbiturate receptor; increase the affinity of GABA for its receptor Enhances inhibitory effect of GABA
33
Zaleplon
BZD like drug Bind to benzodiazepine receptor; increase the affinity of GABA for its receptor Enhances inhibitory effect of GABA
34
Estazolam
Benzodiazepine Bind to benzodiazepine receptor; increase the affinity of GABA for its receptor Enhances inhibitory effect of GABA Decrease release of GABA
35
Zolpidem
BZD like drug Bind to benzodiazepine receptor; increase the affinity of GABA for its receptor Enhances inhibitory effect of GABA
36
Flurazepam
Benzodiazepine Bind to benzodiazepine receptor; increase the affinity of GABA for its receptor Enhances inhibitory effect of GABA Decrease release of GABA
37
Ramelteon
Melatonin receptor agonist
38
Acamprosate
Treats alcohol dependence | Unknown MOA
39
Lorazepam
Benzodiazepine Bind to benzodiazepine receptor; increase the affinity of GABA for its receptor Enhances inhibitory effect of GABA Decrease release of GABA
40
Midazolam
Benzodiazepine Bind to benzodiazepine receptor; increase the affinity of GABA for its receptor Enhances inhibitory effect of GABA Decrease release of GABA
41
Disulfiram
Treats alcohol dependence | Inhibits aldehyde dehydrogenase; causes acetaldehyde accumulation in the blood
42
Oxazepam
Benzodiazepine Bind to benzodiazepine receptor; increase the affinity of GABA for its receptor Enhances inhibitory effect of GABA Decrease release of GABA
43
Naltrexone
Long acting opiate antagonist | Treats alcohol dependence
44
Temazepam
Benzodiazepine Bind to benzodiazepine receptor; increase the affinity of GABA for its receptor Enhances inhibitory effect of GABA Decrease release of GABA
45
Triazolam
Benzodiazepine Bind to benzodiazepine receptor; increase the affinity of GABA for its receptor Enhances inhibitory effect of GABA Decrease release of GABA
46
Chlorpromazine
1st generation antipsychotic | D2 antagonist--decreases effectiveness of DA to produce action potential
47
Aripiparazole
2nd generation antipsychotic High affinity for D2 but also D3, D4, and serotonin receptors Antagonist
48
Fluphenazine
1st generation antipsychotic | D2 antagonist--decreases effectiveness of DA to produce action potential
49
Haloperidol
1st generation antipsychotic | D2 antagonist--decreases effectiveness of DA to produce action potential
50
Lithium
Treatment of mania | MOA unknown
51
Thioridazine
1st generation antipsychotic | D2 antagonist--decreases effectiveness of DA to produce action potential
52
Clozapine
2nd generation antipsychotic High affinity for D2 but also D3, D4, and serotonin receptors Antagonist
53
Olanzapine
2nd generation antipsychotic High affinity for D2 but also D3, D4, and serotonin receptors Antagonist
54
Thiothixene
1st generation antipsychotic | D2 antagonist--decreases effectiveness of DA to produce action potential
55
Carbamazepine
Treatment of mania | Anti-epileptic: targets voltage-gated Na channels in neurons
56
Quetiapine
2nd generation antipsychotic High affinity for D2 but also D3, D4, and serotonin receptors Antagonist
57
Risperiodone
2nd generation antipsychotic High affinity for D2 but also D3, D4, and serotonin receptors Antagonist
58
Valprioc acid
Treatment of mania | Anti-epileptic: targets voltage-gated Na channels in neurons
59
Ziprasidone
2nd generation antipsychotic High affinity for D2 but also D3, D4, and serotonin receptors Antagonist

Pharmacology II (6 decks)

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