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Systemic Pharmacology II > Quiz 2 Material > Flashcards

Quiz 2 Material Flashcards

(57 cards)

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1
Q

Haloperidol

A

First Generation Antipsychotic: D2 antagonist (effects on movement - extrapyramidal side effects)

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2
Q

Estazolam

A

Benzodiazepines: Bind to benzodiazepine receptor that increase the affinity of GABA for its receptor and also decrease the release of GABA

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3
Q

Paroxetine

A

Selective Serotonin Reuptake Inhibitors (SSRIs): Block the reuptake of 5-HT (serotonin) = highly selective

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4
Q

Zolpidem

A

Other Hypnotic Agents (“Benzo-like”): High affinity for the benzodiazepine binding site of GABA receptors (mimicing the effects of Benzodiazepines but with shorter durations of action)

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5
Q

Naltrexone

A

Treatment of Alcohol Dependence: Long acting opiate antagonist

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6
Q

Pentobarbital

A

Barbiturates: Bind to barbiturate receptor that increase the affinity of GABA for its receptor

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7
Q

Escitalopram

A

Selective Serotonin Reuptake Inhibitors (SSRIs): Block the reuptake of 5-HT (serotonin) = highly selective

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8
Q

Clomipramine

A

Tricyclic Antidepressants (TCAs): Block the reuptake of NE and 5-HT (serotonin) by inhibiting the transporter protein

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9
Q

Zaleplon

A

Other Hypnotic Agents (“Benzo-like”): High affinity for the benzodiazepine binding site of GABA receptors (mimicing the effects of Benzodiazepines but with shorter durations of action)

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10
Q

Imipramine

A

Tricyclic Antidepressants (TCAs): Block the reuptake of NE and 5-HT (serotonin) by inhibiting the transporter protein

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11
Q

Eszopiclone

A

Other Hypnotic Agents (“Benzo-like”): High affinity for the benzodiazepine binding site of GABA receptors (mimicing the effects of Benzodiazepines but with shorter durations of action)

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12
Q

Secobarbital

A

Barbiturates: Bind to barbiturate receptor that increase the affinity of GABA for its receptor

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13
Q

Carbamazepine

A

Drugs used to treat Mania and Bipolar Disorder

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14
Q

Midazolem

A

Benzodiazepines: Bind to benzodiazepine receptor that increase the affinity of GABA for its receptor and also decrease the release of GABA

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15
Q

Doxepin

A

Tricyclic Antidepressants (TCAs): Block the reuptake of NE and 5-HT (serotonin) by inhibiting the transporter protein

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16
Q

Desipramine

A

Tricyclic Antidepressants (TCAs): Block the reuptake of NE and 5-HT (serotonin) by inhibiting the transporter protein

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17
Q

Sertraline

A

Selective Serotonin Reuptake Inhibitors (SSRIs): Block the reuptake of 5-HT (serotonin) = highly selective

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18
Q

Duloxetine

A

Serotonin/Norepinephrine Reuptake Inhibitors (SNRIs): Block the reuptake of NE and 5-HT (serotonin) (and more effective if pain is experienced along with depression)

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19
Q

Ziprasidone

A

Second Generation Antipsychotic: Antagonist with high affinity for D2 but also D3, D4, and 5-HT receptors (does NOT have effects on movement)

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20
Q

Tranylcypromine

A

Monoamine Oxidase Inhibitors (MAOIs): Inhibit metabolism of NE, 5-HT(serotonin), and dopamine (and increasing the effectiveness of synaptic transmission by increasing the amount of transmitter replaced per action potential)

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21
Q

Phenobarbital

A

Barbiturates: Bind to barbiturate receptor that increase the affinity of GABA for its receptor

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22
Q

Chlorpromazine

A

First Generation Antipsychotic: D2 antagonist (effects on movement - extrapyramidal side effects)

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23
Q

Citalopram

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A

Selective Serotonin Reuptake Inhibitors (SSRIs): Block the reuptake of 5-HT (serotonin) = highly selective

24
Q

Diazepam

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A

Benzodiazepines: Bind to benzodiazepine receptor that increase the affinity of GABA for its receptor and also decrease the release of GABA

25
Risperidone
Second Generation Antipsychotic: Antagonist with high affinity for D2 but also D3, D4, and 5-HT receptors (does NOT have effects on movement)
26
Temazepam
Benzodiazepines: Bind to benzodiazepine receptor that increase the affinity of GABA for its receptor and also decrease the release of GABA
27
Aripiprazole
Second Generation Antipsychotic: Antagonist with high affinity for D2 but also D3, D4, and 5-HT receptors (does NOT have effects on movement)
28
Amitriptyline
Tricyclic Antidepressants (TCAs): Block the reuptake of NE and 5-HT (serotonin) by inhibiting the transporter protein
29
Flumazenil
Benzodiazepines Antagonist: Antagonist/block the benzodiazepine binding site
30
Alprazolam
Benzodiazepines: Bind to benzodiazepine receptor that increase the affinity of GABA for its receptor and also decrease the release of GABA
31
Clozapine
Second Generation Antipsychotic: Antagonist with high affinity for D2 but also D3, D4, and 5-HT receptors (does NOT have effects on movement)
32
Clorazepam
Benzodiazepines: Bind to benzodiazepine receptor that increase the affinity of GABA for its receptor and also decrease the release of GABA
33
Nortriptyline
Tricyclic Antidepressants (TCAs): Block the reuptake of NE and 5-HT (serotonin) by inhibiting the transporter protein
34
Bupropion
Atypical Antidepressants: Weak dopamine and NE reuptake inhibitor (also help decrease craving and withdrawal symptoms for nicotine)
35
Buspirone
Other Anxiolytic Drug: Serotonin receptor agonist (can treat anxiety but can't induce sedation)
36
Valprioc acid
Drugs used to treat Mania and Bipolar Disorder
37
Fluphenazine
First Generation Antipsychotic: D2 antagonist (effects on movement - extrapyramidal side effects)
38
Mirtazapine
Atypical Antidepressants: Enhances serotonin and NE neurotransmission (block presynaptic alpha-2 receptors) and potent antihistamine activity (sedative)
39
Thiothixene
First Generation Antipsychotic: D2 antagonist (effects on movement - extrapyramidal side effects)
40
Trazodone
Atypical Antidepressants: Weak inhibitor of serotonin reuptake and potent antihistamine activity (sedative)
41
Nefazodone
Atypical Antidepressants: Weak inhibitor of serotonin reuptake and potent antihistamine activity (sedative)
42
Chlordiazepoxide
Benzodiazepines: Bind to benzodiazepine receptor that increase the affinity of GABA for its receptor and also decrease the release of GABA
43
Selegiline
Monoamine Oxidase Inhibitors (MAOIs): Inhibit metabolism of NE, 5-HT(serotonin), and dopamine (and increasing the effectiveness of synaptic transmission by increasing the amount of transmitter replaced per action potential)
44
Ramelteon
Melatonin Receptor Agonist
45
Venlafaxine
Serotonin/Norepinephrine Reuptake Inhibitors (SNRIs): Block the reuptake of NE and 5-HT (serotonin) (and more effective if pain is experienced along with depression)
46
Phenelzine
Monoamine Oxidase Inhibitors (MAOIs): Inhibit metabolism of NE, 5-HT(serotonin), and dopamine (and increasing the effectiveness of synaptic transmission by increasing the amount of transmitter replaced per action potential)
47
Triazolam
Benzodiazepines: Bind to benzodiazepine receptor that increase the affinity of GABA for its receptor and also decrease the release of GABA
48
Quetiapine
Second Generation Antipsychotic: Antagonist with high affinity for D2 but also D3, D4, and 5-HT receptors (does NOT have effects on movement)
49
Protriptyline
Tricyclic Antidepressants (TCAs): Block the reuptake of NE and 5-HT (serotonin) by inhibiting the transporter protein
50
Acamprosate
Treatment of Alcohol Dependence: Poorly understood MOA
51
Oxazepam
Benzodiazepines: Bind to benzodiazepine receptor that increase the affinity of GABA for its receptor and also decrease the release of GABA
52
Lithium
Drug used to treat Mania: MOA not understood (but thought to inhibit two signal transduction pathways)
53
Fluoxetine
Selective Serotonin Reuptake Inhibitors (SSRIs): Block the reuptake of 5-HT (serotonin) = highly selective
54
Flurazepam
Benzodiazepines: Bind to benzodiazepine receptor that increase the affinity of GABA for its receptor and also decrease the release of GABA
55
Lorazepam
Benzodiazepines: Bind to benzodiazepine receptor that increase the affinity of GABA for its receptor and also decrease the release of GABA
56
Thioridazine
First Generation Antipsychotic: D2 antagonist (effects on movement - extrapyramidal side effects)
57
Disulfiram
Treatment of Alcohol Dependence: Inhibits aldehyde dehydrogenase (causes terrible side effects so patients would avoid alcohol to prevent side effects)

Systemic Pharmacology II (5 decks)

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