[quiz 3]

Question 1

Which of the following is an antigenic lipid found in the phospholipid bilayer that covers the human cell?

cholesterol
beta-glucan
ergosterol
cardiolipin

Answer 1

Cardiolipin

Question 2

Ankyrin-spectrin-brand3 of RBCs are an example of which protein membrane?

Answer 2

Integral

Question 3

Which organelle is known to sequester calcium and is also known as the sarcoplasmic reticulum in muscles?

Answer 3

SER

Question 4

Which organelle is the site of O-glycosylation of proteins

Answer 4

Golgi apparatus

Question 5

T/F: the centrosome is a region composed solely of the cylindrical organelle composed mainly of a protein called tubulin in triplets

Answer 5

F

Question 6

The ___ is made up of a pair of centrioles at its center, and is surrounded by pericentriolar material (PCM) that is important for microtubule nucleation

Answer 6

Centrosome

Question 7

___ are a superfamily of related motor proteins that use a microtubule track in anterograde movement. They are vital to spindle formation during cell division in mitotic and meiotic chromosome separation

Answer 7

Kinesin

Question 8

___ is a major intracellular degradation system during fasting that derives its degradative abilities from the ___

Answer 8

Autophagy
Lysosome

Question 9

The pre-RNA and pre-tRNA are processed in the ___ and exits through ___

Answer 9

Nucleolus
Nuclear pore

Question 10

___ are a family of basic proteins that associate with DNA in the nucleus and help condense it into chromatin

Answer 10

Histone

Question 11

Which protein is responsible in release the positive supercoils that form during the unwinding of the DNA helix

Answer 11

DNA gyrase

Question 12

A posttranslational processing and modification whereby newly synthesized proteins are combined with a carbohydrate moiety

Answer 12

Glycosylation

Question 13

It refers to the initial RNA molecule synthesized, with length equivalent to the full length of the DNA transcribe

Answer 13

pre-mRNA or hnRNA

Question 14

What part is spliced out in order to form the final useable form of your pre-mRNA?

Answer 14

introns

Question 15

Which enzyme is found in the lagging strand but not in the leading strand in replication?

Answer 15

DNA ligase

Question 16

What enzyme catalyzes the formation of polypeptide chains

Answer 16

Peptidyl transferase

Question 17

In eukaryotic cells, the elongation step of transcription is performed by ___

Answer 17

RNA polymerase II

Question 18

What is also known as RNA-dependent DNA polymerase and is found in viruses like HIV and the tips of telomeric regions of the DNA

Answer 18

Reverse transcriptase

Question 19

What kind of RNA is involved in gene regulation, for example silencing some of the genes to avoid expression?

Answer 19

siRNA

Question 20

In the generative cell cycle, the diploid (2N) configuration is seen in all the following stages except:

G0
G1
G2

Answer 20

G2

Question 21

During this stage of the generative cell cycle, the cell continues the synthesis of RNA and new proteins. However, at this point, the cell has a tetraploid (4N) configuration

Answer 21

G2

Question 22

In the generative cell cycle, this is considered to be the temporary resting period. No cell division occurs at this point and it has diploid (2N) configuration

Answer 22

G0

Question 23

Which cell is terminal in G0 phase?

Liver cells
Cells of myocardium
Cells of seminiferous tubules post-radiation
Microglia in the brain

Answer 23

Cells of myocardium

Question 24

The ___ is the portion of the chromosome to which proteins that will pull the sister chromatid apart attach

Answer 24

Kinetochore

Question 25

Cohesin breakdown happens during ___

Answer 25

Anaphase

Question 26

Actomyosin ring formation happens during ___

Answer 26

Telophase

Question 27

The cell undergoing mitosis has a tetraploid (4N) chromosomal configuration in all these stages, except: Prophase Metaphase Anaphase Telophase

Answer 27

Telophase

Question 28

At what stage of meiotic division does chromosome crossing over occur?

Answer 28

Prophase I

Question 29

Enumerate the chromosome configuration in the nuclear division in meiosis

Answer 29

Bivalent chromosomes >> Sister chromatids >> Haploid chromosomes

Question 30

In the pachytene stage, which create the genetic diversity?

Answer 30

Genetic recombination

Question 31

The formation in prophase I that causes greater diversity in offspring

Answer 31

Diplotene

Question 32

In human fetal oogenesis, all developing oocytes develop to this stage and are arrested in prophase I before birth. This is referred to as ___ and it lasts until meiosis is ___ to prepare oocyte for ovulation, which happens at puberty or even later

Answer 32

Dichtyotene Resume

Question 33

Which of the following is a mitogen? E2F RbP p14 p53

Answer 33

E2F

Question 34

Which of the following is a tumor suppressor gene? MYC p53 FGFR MAPK

Answer 34

p53

Question 35

If the ATM gene through the p53 protein cannot still repair massive double stranded breaks in the DNA, what processes will happen?

Answer 35

Bax gene triggers apoptosis