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Pharmacology III > Quiz 3 > Flashcards

Quiz 3 Flashcards

1
Q

Which vitamins can potentially cause toxicity to a fetus?

A
  1. Iron
  2. Zinc
  3. Selenium
  4. Vit A
  5. Vit B6
  6. Vit C
  7. Vit D
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2
Q

When do you use Cervidil & what do you monitor, ADRs?

A

Prostaglandin E2
Initiation or continuation of cervical ripening in Pts at or near term

Monitor uterine activity & fetal HR

ADRs

  1. Uterine tachysystole
  2. Hyperstimulation w/ preexisting spontaneous labor
    - inc. fetal compromise
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3
Q

When is Misoprostol used & ADRs?

A

Prostaglandin E1
Relax smooth muscle of cervix

  1. Uterine tachysystole
  2. Uterine rupture - MC w/ previous C-section
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4
Q

When do you use Oxytocin?

A
  1. Induction of labor in Pts w/ a medical condition
  2. Stimulation or reinforcement of labor
  3. Adjunctive therapy in mgmt of abortion
  4. Production of uterine contractions during the 3rd stage of labor
  5. Control of postpartum bleeding
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5
Q

ADRs Oxytocin

A
  1. Uterine rupture

2. Vasopressin-like effect - water intoxication

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6
Q

Why would you use Penicillin during delivery?

A

Get rid of Group B Strep so it isn’t passed to the baby

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7
Q

Why do you give Erythromycin to newborns?

A

Prevent Gonococcal ophthalmia neonatorum

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8
Q

When do you give caffeine citrate?

A

Apnea of prematurity

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9
Q

When do you use Survanta?

A

Kid at risk of RDS

Replaces surfactant

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10
Q

Origins of insulin

A
  1. Bovine
  2. Porcine
  3. E. coli
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11
Q

Rapid-acting insulin, onset, peak & duration

A
  1. Humalog
  2. Novolog
  3. Apidra

O - 5
P - 30-60
D - 3-5h

Given w/ meals

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12
Q

Short-acting insulin, onset, peak & duration

A

Regular insulin

  1. Humilin
  2. Novolin R

O - 30
P - 2-5h
D - 5-8h

Take before meals

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13
Q

Intermediate insulin, onset, peak & duration

A
  1. NPH

O - 1-2h
P - 6-8h
D - 10-12h

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14
Q

Long acting insulin, peak & duration

A
  1. Lantus
  2. Levemir

NO PEAK
D - 24h

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15
Q

How do you dose insulin?

A

0.3-0.8 U/kg

Half dose as Lantus
Other half as regular insulin given before meals

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16
Q

Contraindications to Metformin?

A
  1. Renal impairment
    M SCR >1.5, F >1.4
  2. HF
  3. Uncontrolled respiratory disease
17
Q

How do Sulfonylureas work & ADRs?

A

Secretagogues - inc. amount of insulin being secreted

  1. HA
  2. Nausea
  3. Hypoglycemia
18
Q

ADRs Thiazolidinediones

A
  1. Liver issues
  2. Fluid retention
    Caution w/ Class I & II HF
    DON’t use w/ III or IV
19
Q

ADRs dpp-iv inhibitors

A

Januvia

  1. Nasopharyngitis
  2. URI
  3. Allergic reactions

Dose in renal impairment, CYP3A4

20
Q

ADRs glp-1 receptor agonists

A

Victoza - SubQ

  1. GI
  2. Delay in gastric emptying time
  3. Renal failure & acute renal failure
21
Q

ADRs sglt2 inhibitor

A
  1. HOTN
  2. Hyperkalemia (Careful w/ K-sparing diuretics)
  3. Infections - UTI
  4. Inc. LDL
22
Q

ADRs meglitinide analogs

A

Prandin

  1. Hypoglycemia
  2. Weight gain
23
Q

ADRs alpha-glucosidase inhibitor

A

Precose

  1. Diarrhea
  2. Abdominal pain
  3. Flatulence
24
Q

ADRs Methimazole

A
  1. Agranulocytosis
  2. Nausea, skin pigmentation, parethesias, joint pain/stiffness, hepatitis, nephritis

Risk factors - rule of forties - dose >40 & Pt >40

25
Q

When should you check TSH?

A

35 & q5y after

26
Q

What drug only has T3?

A

Cytomel

27
Q

When should you test TSH after Synthroid therapy?

A

q6-8 wks until stable then q6-12 months

28
Q

How much does 1 grain of amour thyroid equal in Synthroid?

A

100 mcg

29
Q

What are the nonsteroidal compounds with estrogenic properties?

A
  1. Flavones
  2. Isoflavones
  3. Coumestan derivatives
30
Q

Other than hormones, what drug is used for menopause?

A

Paxil to control vasomotor Sx

31
Q

When should you start estrogen therapy in a menopausal woman?

A

Soon after onset of menopause

32
Q

Estrogens for menopause?

A
  1. PremPro
  2. Premarin
  3. Estradiol transdermal patch
33
Q

What is Medroxyprogesterone used for?

A
  1. Endometriosis

2. Abdominal uterine bleeding

Pharmacology III (20 decks)

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