Quiz 3 Parts 1 & 2 Flashcards
(79 cards)
Which hormone used to be called prolactin inhibiting factor?
Dopamine
TSH, PRL, ACTH, GH, FH, LH are released by
Anterior pituitary
TRH, PIF, CRH, GHRH, GIH, GnRH are released by
hypothalamus
Pink staining acidophils of pituitary secrete which hormones
GH, PRL
Dark purple staining basophils of pituitary secrete which hormones
ACTH, TSH, FSH, LH
Where are ADH and oxytocin made, and also where are they later released from?
Made in hypothalamus, released by posterior pituitary
This part of the pituitary resembles neural tissue with intra-axonal neurosecretory granules
posterior pituitary
Another name for ADH
vasopresin
MC cause of hyperpituitarism
Anterior lobe adenoma
How do we classify pituitary adenomas?
functional vs non-functional
Expanding pituitary lesions can compress what nerve structure, leading to what symptom?
Optic chiasm - bitemporal hemianopsia
MC pituitary tumor
Pituitary adenoma
MC tumor of brain
Pituitary adenoma
How do you differentiate a macro- from micro-adenoma?
> 10mm = macroadenoma.
Silent and hormone negative adenomas are more likely to be macro or micro when found?
Macro - lack endocrine abnormalities that would alert patient
Non-functioning tumors may also be referred to as this (relates to how it reacts to staining)
chromophobic
Usually just one cell line increases in pituitary adenoma. What is the MC subset of a pit. adenoma? (it is also the MC functioning and MC cause of endocrine problems)
Prolactinoma
T/F - a typical pituitary adenoma is soft, well-circumscribed and confined to the sella turcica
T
Microscopy reveals small round cells with uniformly round nuclei and pink to blue cytoplasm. Cells arranged in nests or cords and with prominent vascularity
pituitary adenoma
This tumor’s presenting sxs usually are limited to HA, visual field defects, cranial nerve deficits, possibly hypopituitarism
Non-functioning pituitary adenoma
T/F prolactinomas tend to be weakly acidophilic or chromophobic (sparsely granulated)
T
Are men more likely to have a micro or macro adenoma?
macro - their sx picture is nonspecific - low libido
Pituitary adenomas are associated with which MEN syndrome?
MEN 1
this MEN syndrome has parathyroid adenomas, entero-pancreatic tumors, pituitary adenomas
MEN1