Quiz 5

Question 1

A Pt is taking sumatriptan…what other drugs should they avoid?

Answer 1

MAOIs

Question 2

ADRs ergot derivatives

Answer 2

1. N&V
2. Leg weakness - muscle spams
3. Numbness & tingling in fingers & toes
4. CV - bradycardia, EKG changes, HTN, ischemia

Question 3

Can you use triptans & ergot derivatives together?

Answer 3

No - not w/in 24 h

Question 4

Which drug comes from rye seed?

Answer 4

Ergot derivatives

Question 5

What would you use if you had a tension/muscle contraction HA?

Answer 5

Fioricet - Butalbital, acetaminophen & caffiene

Causes resp. depression

Question 6

When do you use migraine prophylaxis meds?

Answer 6

1. HA interferes w/ daily routine
2. Meds contraindicated, ineffective, overused or bad side effects
3. Frequent migraines
4. Uncommon migraine types
5. Cost
6. Pt preference

Question 7

Common migraine prophylaxis meds

Answer 7

1. Beta blockers - propranolol & timolol
2. TCA - amitryptylline
3. Antiseizure meds - topiramate & valproate
4. Neuromuscular blockade - onabotulinumtoxin A

Question 8

What to watch with anti-epileptic drugs

Answer 8

Inc. metabolism of 
1. Chemo agents
2. Corticosteroids
3. Theophylline
4. Warfarin 
Reduced plasma levels of 
5. Cyclosporine
6. Digoxin
7. Haloperidol
8. Oral contraceptives

Question 9

What drug to use w/ primary generalized tonic-clonic seizures?

Answer 9

Valproate

Question 10

What drug to use w/ partial seizure?

Answer 10

Carbamazepine

Question 11

What drug to use with absence seizure?

Answer 11

1. Ethosuximide

2. Valproate

Question 12

What drug to use with atypical absence, myoclonic or atonic seizure?

Answer 12

Valproate

Question 13

ADRs anti-epileptic drugs

Answer 13

1. Suicide

2. SJS

Question 14

Tx status epilepticus

Answer 14

1. Ativan
2. Fosphenytoin
3. Phenytoin sodium