Quiz Shit

Question 0

What’s one example of traits being changed by environment?

Answer 0

Minnesota twin study.

Height.

Question 1

How can you dissect a genome?

Answer 1

True breeding and inbred strains

Can control environment through incubators greenhouses etc

Question 2

What is concordance?

Answer 2

Calculate the percentage of time a twin has the same trait as the other.

Question 3

What is the use of single nucleotide polymorphism?

Answer 3

To look for a pattern that correlates with a health outcome.
(Snap is close enough that during crossing over ,that the snp and gene of interest travel together.

Question 4

What is the rate limiting factor that controls DNA

Answer 4

RNAP

Question 5

What does the RNAP need?

Answer 5

A promoter to bind to

Question 6

What needs to happen for RNAP to bind?

Answer 6

The histones and nucleosomes need to loosen by was of the addition of an acetyl group to make the histone neutral.

Question 7

What is methylation

Answer 7

The Cp G “island” is over represented and is subject to enzymatic modification or removing CH3 of cytokines.
RNAP binds to methylated Cs do that modification prevents expression of genes.

Question 8

Histone and primer modification is referred to as….

Answer 8

Epigenetic regulation

Question 9

What happens in cloned mice with no fertilization(epigenetics)

Answer 9

30-60% bigger because IGF is not suppressed

Question 10

What is an example of epiagenetic regulation?

Answer 10

Shutting off of X chromosome. Doesn’t allow each tissue to function normally.
Requires help of transcription factors general and regulatory.

Question 11

Prokaryote gene regulation?

Answer 11

Not highly compacted-default of gene is off.
RNAP binds to promoter and is assisted by an activator.
Neg regulation- needs a depressor protein. Requires a co repressor.
Activators and repressors ally present but coactivators, co repressors and inducers respond to environmental cues.

Question 12

What is an operant?

Answer 12

Gene regulation that encodes multiple proteins on the same transcript.

Question 13

Describe the tryptophan Oberon

Answer 13

Encodes 5 enzymes that are required to make tryptophan from scratch. Default is on so neg regulation is used to turn it off.
Tryptophan and corepressor causes confrontational change so repressor binds to operon impeding RNAP from transcribing genes.