RADBIOLOGY (CELLS) Flashcards

(52 cards)

1
Q

study of the effect of ionizing radiation

A

Radiobiology

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2
Q

what are molecules

A

they are atoms of various elements combined together

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3
Q

what are the 6 levels of organization?

A
Chemical Level
Cell Level
Tissue Level
Organ Level
Organ Systems Level
Organism Level
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4
Q

Define Compound

A

Any quantity of one type of molecule; elements that are combined together

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5
Q

Whats the formula for the principle quantum no?

A

2 (n)^2

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6
Q

How do you know an atom is stable?

A

When there is an equal no. of protons and electrons

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7
Q

How many electrons can the most outer shell contain?

A

8

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8
Q

What are the 2 kinds of compounds?

A

Covalent & Ionic

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9
Q

Define Covalent C.

A

Covalent C. share one or more pairs of electrons

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10
Q

Define ionic c

A

Ionic C are held together by the force of attraction between opposite charges

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11
Q

Who and when was the word cell coined

A

ROBERT HOOKE, 1665

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12
Q

Who and when described the first living cell using a microscope

A

ANTON VAN LEEUWENHOEK, 1673

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13
Q

Who are the authors of cell theory

A

SCHWANN & SCHNEIDER, 1838

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14
Q

What are the different cell parts?

A
Cell
Cell Membrane
Cytoplasm
Nucleus
Nuclear Membrane
Ribosomes
Lysosomes
ER
Mitochondria
Golgi Bodies
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15
Q

What is a cell?

A

Building block of all organisms, comes from pre-existing cells

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16
Q

It makes bulk of the cell and contains great quantities of all molecular components

A

Cytoplasm

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17
Q

What is a portion of the cytoplasm?

A

Cytosol

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18
Q

What is the cytosol?

A

site of many chemical reactions required for the cell’s existence

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19
Q

What is the mitochondria?

A

Bean-like structure; where molecules are digested to produce energy for the cell; engine of the cell

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20
Q

What is the ER?

A

Series of channels that allows the nucleus to communicate w/ the cytoplasm

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21
Q

These are small dot-like structures and where the protein-synthesis take place

22
Q

These are pea-like sacs that are capable of digesting cellular fragments & sometimes the cell itself

23
Q

Principal Molecular component that carries DNA

24
Q

What are the highest and lowest atomic composition of the body and by how much?

A

H 60%

Other Trace elements 0.8%

25
What are the highest and lowest tissue composition of the body?
Muscle 43% | Skin 3%
26
What happens if molecular synthesis is damaged?
Cell may malfunction and die
27
What is protein synthesis?
contains a molecular code that identifies w/c proteins the cell will make
28
What are macromolecules?
Very large molecules
29
What is an organic mole.
life supporting and contain carbon (carbs, lipids, proteins)
30
One of the rarest mole. and considered to be the most critical & radiosensitive target mole.
NUCLEIC ACID
31
2 kinds of metabolism
Catabolism | Anabolism
32
Define Cata. and Ana
CATA - breaking down into small units of macromole. Ana - build muscle mass
33
Types of macromolecules
Proteins, Lipids, Carbs, Nucleic Acid
34
Makes up 15% of the body and is a long chain of macromole connected by peptide bonds
Proteins
35
Mass of protein
``` 50% C 20% O 17% N 7% H 6% other elements ```
36
Roles of Proteins
Provide structure and support Function as enzymes Function as hormones Function as antibodies
37
Composed solely of C,H,O and are present in all tissues of the body
Lipids (Fats)
38
What are the 2 smaller molecules of Lipids?
Glycerol and Fatty acid
39
Similarity of Carbs to lipids
Composed solely of C,H,O but structured differently
40
Role of Lipids
Serve as thermal insulator from the environment | serve as fuel by providing energy storage
41
Roles of carbs
serve as fuel for metabolism | provide shape and stability into the structure of cells and tissues
42
What are nucleic acid?
v. large & extremely complex macromole. made up of DNA & RNA
43
Where are DNA & RNA located?
DNA - nucleus | RNA- principally in the cytoplasm but can also be found in the nucleus
44
What is cell proliferation?
single cell / group of cells to reproduce & multiply in nos.
45
2 kinds of cells
SOMATIC -tissue cells | GENETIC - oogonium & spermatogonium
46
2 kinds of cell division
Mitosis and Meiosis
47
Difference between MITOSIS & MEIOSIS
MITOSIS - undergoes 1 cell division - only has 2 phases of cell division (Inter, M) - produces 2 daughter cells - only somatic cells undergo this process MEIOSIS - undergoes 2 cell divisons - has 3 phases of cell division (Inter, M1, M2) - produces 4 daughter cells - only genetic cells undergo this process
48
Process of Mitosis
``` A. Interphase -G1 - Synthesis -G2 B. Mitosis -Prophase -Metaphase -Anaphase -Telophase ```
49
Process of Meiosis
A. Interphase (G1, Synthesis, G2) B. Meiosis I (PMAT 1) C. Meiosis 2 (PMAT 2)
50
What is the dna synthesis phase where the dna is replicated into 2?
Synthesis phase
51
How many chromosomes do we start with meiosis?
23 chromosomes
52
Why is the s phase in meiosis not as relevant as it is in mitosis?
it is because there is no dna replication happening in meiosis