Rajan- Bleeding and coagulation Flashcards
1
Q
normal aPTT
prolonged PT
A
liver disease
warfarin
Vit. K def.
Low factor 7
2
Q
prolonged aPTT
normal PT
A
heparin
lupus
anticoagulants
low 8, 9, 11, 12, HMWK, prekallikrein
3
Q
prolonged PT and PTT
A
liver disease warfarin vit. deficiency low 5, 10, fibrinogen, prothrombin citrate effect due to high hematocrit
4
Q
increased bleeding time
A
von Willebrand disease thrombocytopenia platelet aggregation defect collagen vascular disorders aspirin like drugs
5
Q
normal bleeding time
A
1-6 min
6
Q
normal PTT
A
25-35 seconds
7
Q
normal PT/INR
A
11-15 seconds
8
Q
increased PTT
A
hemophilia A and B, DIC, liver disease, vit. K def., coumadin
9
Q
increased PT/INR
A
DIC, liver disease, vit. K deficiency, coumadin
10
Q
increased factor VIII
A
liver disease
11
Q
decreased factor VIII
A
hemophilia A, vW disease, DIC
12
Q
decreased factor IX
A
hemophilia A
13
Q
decreased factor V
A
liver disease, DIC
14
Q
desmopressin (DDAVP)
A
increases factor VIII
hemoarthrosis
Tx: hemophilia A
NOT for hemophilia B
15
Q
hemophilia C
A
Rosenthal’s Disease
ashkenazi jews
Tx: FFP
