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Question 1

143. Date of a papillary lines formation:
     a)6-7 week - an expression of genes;
     b) 8-10 week - accumulation of inducers for an expression of genes determining lines;
     c) 10-24 week - formation of papillary lines;
     d) 24-40 week - formation of a skin as tactile organ.

Answer 1

b) 8-10 week - accumulation of inducers for an expression of genes determining lines;
c) 10-24 week - formation of papillary lines;
d) 24-40 week - formation of a skin as tactile organ.

Question 2

159. Optimal time of carrying out chorionopexia at prenatal diagnostics:
     a) 6-7week of pregnancy
     b) 12-13 week of pregnancy;
     c) 13-14 week of pregnancy;
     d) 14-16 week of pregnancy.

Answer 2

a) 6-7week of pregnancy

Question 3

160. Optimal time of carrying out amniocentesis at prenatal diagnostics:
     a)6-7 week of pregnancy;
     b) 12-13 week of pregnancy;
     c) 14-16 week of pregnancy;
     d) 18-20 week of pregnancy.

Answer 3

c) 14-16 week of pregnancy;

Question 4

163. Causes of phenylketonuria development:
     a)deficiency of an enzyme oxidase a homogentistic acid;
     b) deficiency of an phenylalanindehydrxylase enzyme;
     c) accumulation in a blood phenylpirovinici acids.

Answer 4

b) deficiency of an phenylalanindehydrxylase enzyme;
c) accumulation in a blood phenylpirovinici acids.

Question 5

164. The causes of development alkaptonuria:
     a)deficiency or absence of an enzyme oxydase a homogentistic acid;
     b) absence of an enzyme of a tyrosinase;
     c) absence of metabolism a homogentistic acid up to end products of disintegration.

Answer 5

a)deficiency or absence of an enzyme oxydase a homogentistic acid;
c) absence of metabolism a homogentistic acid up to end products of disintegration.

Question 6

168. Characteristics of hemochromatosis:
     a)selective accumulation Ferri lactas in cells of a liver, hemadens, a cardiac muscle;
     b) the increased contents Ferri lactas in a blood;
     c) drop of Ferri lactas contents in a blood;
     d) development of a cirrhosis of the liver, increased xanthopathy.

Answer 6

a)selective accumulation Ferri lactas in cells of a liver, hemadens, a cardiac muscle;
b) the increased contents Ferri lactas in a blood;
d) development of a cirrhosis of the liver, increased xanthopathy.

Question 7

130. Examples of semilethal mutations of human:
     a)daltonism;
     b) Dawn syndrome;
     c) trisomy on X-chromosome;
     d) hemophilia;
     e) muscular dystrophia Duchenne.

Answer 7

b) Dawn syndrome;
d) hemophilia;
e) muscular dystrophia Duchenne.

Question 8

131. Examples of lethal mutations of human:
     a)brachydactyly in a homozygous state;
     b) set of symptoms УО;
     c) Edwards - Smith’s set of symptoms;
     d) set of symptoms Pattaw’s;
     e) Konovalov-Wilson disease.

Answer 8

a)brachydactyly in a homozygous state;
b) set of symptoms УО;
c) Edwards - Smith’s set of symptoms;
d) set of symptoms Pattaw’s;

Question 9

140. Potency of a twin’s method of anthropogenetics:
     a)specification of the list of hereditary diseases;
     b) determination of a role of hereditary factors and environment in illness exhibiting;
     c) carrying out of well-timed prophylaxis of illness of one of twins at disease manifestation in the second of ones.

Answer 9

a)specification of the list of hereditary diseases;
b) determination of a role of hereditary factors and environment in illness exhibiting;
c) carrying out of well-timed prophylaxis of illness of one of twins at disease manifestation in the second of ones.

Question 10

141. Potency of a population-statistical method of anthropogenetics:
     a)determination of heterozygotes number in a population;
     b) the decision of a question of medical, medicamental and diagnostic maintenance in the population;
     c) revealing of drift of genes in a population.

Answer 10

a)determination of heterozygotes number in a population;
b) the decision of a question of medical, medicamental and diagnostic maintenance in the population;
c) revealing of drift of genes in a population.

Question 11

142. Potency of dermatoglific method of anthropogenetics:
     a)studying of individual variability;
     b) diagnosis of the chromosomal diseases;
     c) revealing of a heterozygous carriage of a pathological gene.

Answer 11

a)studying of individual variability;
b) diagnosis of the chromosomal diseases;

Question 12

154. Opportunities of the express-method for sex chromatin definition:
     a)finding hereditary diseases linked to change of structure of sex chromosomes;
     b)finding hereditary diseases linked to change of sex chromosomes number;
     c) sex determination at a hermaphroditism and transsexualism;
     d) sex determination at judicial examination.

Answer 12

a)finding hereditary diseases linked to change of sex chromosomes number;
c) sex determination at a hermaphroditism and transsexualism;
d) sex determination at judicial examination.

Question 13

156. Opportunities of a biochemical method:
     a)finding hereditary diseases of a metabolism;
     b) finding chromosomal hereditary diseases;
     c) allows to define phylum and variant of inheritance.

Answer 13

a)finding hereditary diseases of a metabolism;

Question 14

157. At what levels of exhibiting of gene action and how hereditary diseases of a metabolism are diagnostic?
     a)on molecular - structure and quantity of initial materia;
     b) on cellular - defective enzymes;
     c) on ontogenetic - intermediate products of metabolism;
     d) on histological - antigens.

Answer 14

a)on molecular - structure and quantity of initial materia;
b) on cellular - defective enzymes;
c) on ontogenetic - intermediate products of metabolism;

Question 15

161. Opportunities of a molecular-genetic method:
     a)finding hereditary diseases of a metabolism;
     b) definition of changes of structure and function of nucleic acids;
     c) abjection of genes and injection them in a cell.

Answer 15

b) definition of changes of structure and function of nucleic acids;
c) abjection of genes and injection them in a cell.