Flashcards in Rapid Review 2 Uworld/Rx Deck (20):
Normacytic anemia and hypercalcemia. Bone biopsy shows the cell type shown. Dx?
What would you find on x-ray?
Add pics FA pg 419
Bone marrow with >30% plasma cells is diagnostic for Multiple Myeloma.
Punched out lytic lesions
Stacks of RBC and increased ESR?
What is the pathophysiology behind the lytic bone lesions seen in Multiple Myeloma?
Neoplastic cells secrete IL-1 (osetoclast activating facotr) and IL--6
This leads to bone re-absorption
Pregnant woman with nauseo and lightheadedness at bed time. What is the pathophysiology behind her symptoms?
She has supine hypertension syndrome:
Compress IVC--> decrease in venous return--> reduced preload--> decreased cardiac output--> hypertension
Impaired ornathine transport requires what type of dietary restriction?
Treatment for rabies
The presence of odynophagia is indication of what ? How does it rule out Barrets?
pain with swolloging indicated an errosive process and ulcer formation. Barrett's intestinal metaplasia occurs without pain but with dysphagia and weight loss.
History of heartburn with acute odynophagia will indicate formation of what?
What cells are a product of the immune response against TB?
CD5 Th1 helper cells.
Oxidase negative, Non lactose fermenting gram negative rods that forms acid (not oxygen) during glucose fermentation. Ferment glucose without gas production, do not generate hydrogen sulfide when grown on tripple sugar iron agar and can not replicate with refrigeration temperatures.
Shigella. If it produces H2s then Salmonella
Initially watery diarrhea that turns bloody.
E. coli that does not ferment sorbitol or produce glucuronidase. MOA of toxin?
Inactivates ribosomal subunits
toxin that leads to increase intracellular cyclic GMP
ETEC (ST) and Yersenia (enerotoxin)--> watery diarrhea and electrolyte loss
Toxin that disrups cytototocin via actin depolymerization leading to diarrhea and pseudomembranous colitis
C Diff toxin B
Treat with Metronidazole and Vanco
Toxins that lead to increase in intracellular cAMP
1. LT ETEC
2. Bordetella pertussis
and C. Jejuni enterotoxin
Toxin that uses EF-2 via catalyzation of ADB ribosylation
C. Dip--> pseudomembranes
Pseudomonas --> death
45 yr old female pt with heavy painful period. Uniformly enlarged uterus and secretory endometrium
Adenomyosis with endometrial tissue into uterine myometrium
Hyperplastic growth of endometrial glands and stroma
Young, asymptomatic patient with soft ejection murmur at the right secong intercostal space. What pathology results in this?
Bicuspid Aortic Valve