Flashcards in Flash fact 3 Deck (17):
Pt with IL-12 receptor deficiencies suffer from what type of infection?
Explain the pathophysiology behind why this occurs.
Mycobacterium: refer to board prep document for pathway.
IL-y is indicated for treatment
What is the most important host factor in preventing re-infection of influenza?
Antibodies against hemaggluttinin
Why is B12 deficiency more likely in someone with strict vegan diet than complete gastrectomy?
depletion occurs over a long period of time which probably wouldn't occur in someone with this surgery becasue they would be given supplements.
Insulin independent tissues and transporters
Brain, kidney, intestine, liver, RBC
Glut 1-5 except for 4
Insulin mediated glucose transport
Glut 4: Muscle and Adipocytes
Blue toe, livedo reticularis and normal peripheral pulses
Signs of emboli
Signs of embolism following invasive vascular proceedure (angiography, etc) is suspicious for____. What would you find in a histo section of the kidney?
partially or completely occluded arterial lumen with needle shaped cholesterol clefts within the atheromatous thrombus.
Antiviral medication that doesn't require intracellular activation by viral or cellular kinass
Bypassing P labler--> doesn't need to be phosphorylated by viral enzyme
What drug withdraw causes acute depression accompanied by fatigue, vivid dreams, hypersomnia and hyperphagia
Described as lethargic and dysphoric
Ototoxicity in pt being treated for HF
pt being treated for atrial fibrillation and CHF presents with with cardiac arrhythmia and nonspecific GI symptoms (nausea, vomiting), neurological, visual symptoms
Inhibition of na-K-ATPase--> increased intracellular sodium and calcium
Increased Vegal Tone
Pt with lymphandenopathy that fluctuates in size?
"Waxing and Waning"
Earliest manifestation of diabetic nephropathy
Analysis of partially replicated DNA fragments shows uracil. Which bacterial enzyme mediates this?
This is asking which enzyme involved with DNA synthesis catalyses the formation of RNA strands.
Primase: An RNA Pol, synthesises short RNA primer using
12 year old boy with intellectual disability. Cytogenetic studies show a small gap near the tip of the long arm of the X-Chromosome. How would the pt phenotypically present. Descibe the pathophysiology of this dz.
This is describing fragile X syndrome:
Defect in expansion of CCG on the FMR1 gene