RAT #14 - Overview of Regulating Gene Expression Flashcards
General transcription factors are?
a. regulatory DNA sequences that bind to the promoter site
b. regulatory proteins that bind to a promoter site
c. regulatory proteins that bind to enhancers or silencers
d. regulatory sequences that bind to a protein
e. regulatory bases that bind to the promoter
Selected Answer: [None Given]
Translational regulatory proteins may shut down translation of processed mRNA
transcripts by?
a. excising a short sequence of nucleotides
b. removing the poly-A tail
c. reinserting introns into the transcript
d. binding to the 3’ UTR
e. binding to 5’ UTR
Selected Answer: [None Given]
The role of methylation of DNA is now viewed as?
a. preventing mutations
b. complexing with enhancers to prevent transcription
c. interfering with transcription by blocking base pairing between cytosine and guanine
d. is irrelevant to gene transcription
e. interfering with transcription by forming a complex of proteins at transcriptionally-relevant locations
Selected Answer: [None Given]
Transcription factors appear to be unable to bind to a nucleosome because?
a. enhancers are placed in an inaccessible position
b. of histones positioned over promoters
c. activators are inhibted by the configuration
d. nucleosomes are especially vulnerable to repressors
e. of inhibition of RNA Polymerase
Selected Answer: [None Given]
Which of the following is NOT an example of the control of gene expression that occurs AFTER transcription?
a. circularization of the mRNA transcript
b. the length of time mRNA lasts before it is degraded
c. modification of a polypeptide
d. RNA processing before mRNA exits from the nucleus
e. gene methylation
Selected Answer: [None Given]
All ofthe following are ways eukaryotic genes are regulated AFTER the mRNA transcript
is made EXCEPT?
a. alternative patterns of intron removal
b. interaction between enhancers and regulatory transcription factors
c. the addition of chemical groups to a protein product
d. increasing the stability of mRNA so it lasts longer
e. temporary inactivation of a protein by binding of an allosteric inhibitor
Selected Answer: [None Given]
Which of the following is NOT a form of regulating phenotype?
a. transcriptional regulation
b. posttranscriptional regulation
c. translational regulation
d. regulating DNA synthesis
e. regulating protein function
Selected Answer: [None Given]
All of the following are examples of transcriptional control of gene expression EXCEPT?
a. the removal of introns and splicing of exons
b. the addition of methyl groups to bases of DNA
c. the binding of activators to enhancers
d. the binding of transcription factors to promoters
e. the condensing of DNA to form heterchromatin
Selected Answer: [None Given]
Translational regulation occurs in?
a. the nucleus
b. the cytoplasm
c. lysosomes
d. the mitochondria
e. the golgi apparatus
Selected Answer: [None Given]
The primary RNA transcript of the chicken ovalbumin gene is 7700 nucleotides long, but
the mature mRNA that is translated on the ribosome is 1872 nucleotides long. This size
difference occurs primary as a result of?
a. capping
b. splicing
c. methylation
d. removal of polyA tails
e. cleavage of polycistronic mRNA
Selected Answer: [None Given]
