RAT #19 - Vesicular Trafficking - (Mechanism)

Question 1

Which of following Molecules is responsible for Determining which Proteins are to be Transported by the Transport Vesicle?

a. Cargo proteins
b. SNAP proteins
c. Adaptor proteins
d. SNARE proteins
e. GTP-binding proteins

Answer 1

c. Adaptor proteins

Question 2

COP I-coated Vesciles travel in which direction?

a. in no direction
b. Retrograde only
c. Retrograde & Anterograde
d. Anterograde only

Answer 2

b. Retrograde only

Question 3

What is Function of Coat Proteins in Vesicular Transport?

a. to Drive vesicle budding by distorting membrane conformation.
b. to Aggregate proteins that are to be stored for future secretion
c. to Select proteins that are to be carried by the Transport vesicle.
d. to Target Transport vesicle to its appropriate destination.
e. to Promote fusion between the Transport vesicle & the Membrane of the Target structure or Organelle.

Answer 3

a. to Drive vesicle budding by distorting membrane conformation.

Question 4

What other Key Component of Cell is required for Vesicular Trafficking to occur?

a. Nucleus
b. Ribosomes
c. Smooth Endoplasmic Reticulum
d. Cytoskeleton
e. Peroxisomes

Answer 4

d. Cytoskeleton

Question 5

The sequence Lys-Asp-Glu-Leu serves as a Retention Signal for ER proteins by binding to Lys-Asp-Glu-Leu receptors that:

a. Transport the Proteins from Plasma Membrane back to Rough ER
b. Hold the Proteins in both the Rough ER & Smooth ER
c. Transport the Proteins from Golgi apparatus back to Rough ER
d. Hold the Proteins in the Rough ER
e. Holds the Proteins in the Smooth ER

Answer 5

c. Transport the Proteins from Golgi apparatus back to Rough ER

Question 6

Lysosomal Proteins are MARKED by Adding a Phosphate to a?

a. Galactose group
b. Glucose group
c. Serine group
d. Mannose group
e. Lactose group

Answer 6

d. Mannose group

Question 7

The Proteins SELECTED for TRANSPORT in Transport Vesicles are called?

a. Adaptor proteins
b. Transported proteins
c. Cargo proteins
d. Vesicle proteins
e. Sample proteins

Answer 7

c. Cargo proteins

Question 8

What Molecule MEDIATES Targeting of Transport Vesicle?

a. NSFs
b. Rab’s
c. SNAPs
d. ARFs
e. SNAREs

Answer 8

b. Rab’s

Question 9

Lysosomal Proteins are Transported FROM the trans-Golgi to Lysosomes via?

a. COP I-coated vesicles
b. Non-protein-coated vesicles
c. Clatherin-coated vesicles
d. SNARE-coated vesicles
e. COP II-coated vesicles

Answer 9

c. Clatherin-coated vesicles

Question 10

The Name given to the Organelle or Cellular Location from where a Transport Vesicle is LEAVING (starting location):

a. Parent organelle
b. Initiator organelle
c. Departure organelle
d. Starting organelle
e. Target organelle

Answer 10

a. Parent organelle