RBC Indices & Anemia

Question 0

What are symptoms of anemia?

Answer 0

Lethargy
Hypotension
Tachycardia
Dyspnea
Pallor
Palpitations

Question 1

What does anemia mean?

Answer 1

Without blood

Question 2

How do we measure anemia?

Answer 2

CBC

H&H

Question 3

How do we classify anemia?

Answer 3

RBC indices
Diet
Deficiencies - B12, Fe

Question 4

What are types of laboratory measures of anemia?

Answer 4

RBC count
Hemoglobin
Hematocrit

Question 5

What is the hemoglobin reference range for male adults?

Answer 5

14-18 g/dL

Question 6

What is the hemoglobin reference range for female adults?

Answer 6

12-16 g/dL

Question 7

What is the hematocrit reference range for males?

Answer 7

42-54%

Question 8

What is the hematocrit reference range for females?

Answer 8

36-46%

Question 9

How is hematocrit measured?

Answer 9

Packed cell volume

Question 10

How is hematocrit (Hct) calculated?

Answer 10

RBC count & average cell size

Question 11

When plasma is low, is there a high or low level of blood cells?

Answer 11

High

Question 12

When the amount of blood cells is low, is there a high or low amount of plasma?

Answer 12

High

Question 13

What is the formula for hematocrit?

Answer 13

Hemoglobin x 3 = hematocrit +/- 3

Question 14

What is the hematocrit if the hemoglobin is 10?

Answer 14

10 x 3 = 30 +/- 3

Question 15

Is this expected?
Hb = 12.5 g/dL
Hct = 37%

Answer 15

Yes

Question 16

Is this expected?
Hb= 10 g/dL
Hct = 37%

Answer 16

No

Question 17

What help classify RBCs?

Answer 17

Size & Hb content/concentration

Question 18

What are calculations that are used to classify anemia?

Answer 18

MCV - mean cell volume
MCH - mean cell hemoglobin
MCHC - mean cell hemoglobin concentration

Question 19

What is the MCV (mean cell volume) reference range?

Answer 19

80-100 fL

Question 20

How is the MCV measured?

Answer 20

Measured directly by electrical impedance

Question 21

How is MCV calculated/what is the formula?

Answer 21

MCV = Hematocrit (%) x 10 / RBC (10ˆ12/L)

Question 22

What is MCV interpreted as (3 types)?

Answer 22

Normocytic
Microcytic
Macrocytic

Question 23

What is RDW?

Answer 23

Red cell distribution width

Question 24

What does RDW measure?

Answer 24

Anisocytosis

Question 25

What is anisocytosis?

Answer 25

Cell population are different sizes

Question 26

What is the normal reference range of RDW?

Answer 26

11.5-14.5

Question 27

What does MCH stand for?

Answer 27

Mean corpuscular hemoglobin

Question 28

What does MCH measure?

Answer 28

Average hemoglobin per RBC

Question 29

What is the reference range of MCH?

Answer 29

27-31 pg

Question 30

What is the formula for MCH?

Answer 30

MCH = Hemoglobin (g/dl) x 10 / RBC (10ˆ12/L)

Question 31

What does MCHC stand for?

Answer 31

Mean cell hemoglobin concentration

Question 32

What is the reference range for MCHC?

Answer 32

32-36%

Question 33

What is MCHC used for?

Answer 33

Used with MCV to classify erythrocytes

Question 34

What are the classifications of erythrocytes based on MCHC?

Answer 34

Normochromic Hypochromic Hyperchromic

Question 35

What is the formula for MCHC?

Answer 35

MCHC = Hemoglobin (g/dl) x 100 / HCT (%)

Question 36

MCV - 80-100 MCHC 32-36 What are the possible causes?

Answer 36

Acute or chronic blood loss Bone marrow failure Hemolytic anemia Leukemia

Question 37

MCV - >100 MCHC - 32-36 What are the possible causes?

Answer 37

Megalobastic anemia | Macrocytic anemia

Question 38

MCV - <32 | What are the possible causes?

Answer 38

Iron deficiency Thalassemia Lead poisoning Chronic infection

Question 39

What are the possible causes of normocytic normochromic anemia?

Answer 39

Renal failure Leukemia Early iron deficiency

Question 40

What size is the RBC of normocytic normochromic anemia?

Answer 40

Similar to the nucleus of a lymphoocyte

Question 41

What are the causes of microcytic hypochromic anemia?

Answer 41

Iron deficiency Thalassemia minor Lead poisoning

Question 42

What do the RBCs look like when a person has microcytic hypochromic anemia?

Answer 42

Cells are small | Large central pallor

Question 43

What are the causes of macrocytic normochromic anemia?

Answer 43

Megaloblastic anemia (B12 or folate deficiency) Alcoholism Liver disease

Question 44

In polychromasia the Wright's stain stains what part of the cell?

Answer 44

RNA

Question 45

In polychromasia the methylene blue stain colors the cells what color?

Answer 45

Blue

Question 46

In peripheral blood smears what type of cells are present (shape)?

Answer 46

Target cells

Question 47

What does poikilocytosis mean?

Answer 47

RBCs are different shapes