Regulation of RBF & ECF

Question 0

renal blood flow vasodilators (4)

Answer 0

ANP
glucocorticoids
NO
prostaglandins

Question 1

vasoconstrictors of renal blood flow (5)

Answer 1

a1 sympathetic stimulation
Angiotensin II
ADH
ATP
endothelin

Question 2

increasing resistance of the afferent arteriole will: (3 things)

Answer 2

decrease Pgc, GFR, RBF

Question 3

increasing resistance of the efferent arteriole will (2 things)

Answer 3

increase GFR and RBF

Question 4

increasing resistance of both the afferent and the efferent arteriole will (2 things)

Answer 4

no change GFR

decrease RBF

Question 5

aldosterone release is stimulated by (2)

Answer 5

increased [AngII]

increased plasma [K+]

Question 6

stimulates Na+ absorption in the late distal tubule and collecting duct

Answer 6

aldosterone

Question 7

vasoconstrictor; favors salt retention, thirst, aldosterone release, and elevation of arterial BP

Answer 7

Angiotensin II

Question 8

this hormone stimulates Na+/H+ exchange in the proximal tubule?

Answer 8

Angiotensin II

Question 9

Angiotensin II favors (4 things)

Answer 9

Na+H+ exchange: salt retention
elevation of arterial BP
thirst
aldosterone release

Question 10

increases GFR, decreases NaCl reabsorption by the CD

Inhibits secretion of renin & aldosterone

Answer 10

ANP

Question 11

how does ANP increase GFR?

Answer 11

dilates the afferent arteriole

constricts the efferent arteriole

Question 12

what chemical inhibits secretion of renin & aldosterone?

Answer 12

ANP

Question 13

effects of ADH (3)

Answer 13

increased Na+K+2Cl- activity
increased urea permeability
aquaporin insertion in the CD

Question 14

what stimulates ADH release (2)

Answer 14

increased plasma osm

decreased plasma vol

Question 15

causes of reduced Osmolar clearance (3)

Answer 15

decreased GFR
increased aldosterone
Conn’s syndrome & diseases

Question 16

causes of increased osmolar clearance (2)

Answer 16

diuretic use

decreased aldosterone

Question 17

low ADH
high plasma Osm
decreased urine Osm

Answer 17

diabetes inspidus

Question 18

low aldosterone
hyponatremia
increased ECF vol.
concentrated urine

Answer 18

SIADH

Question 19

stimulates K+ movement into the cell (3)

Answer 19

B2 stimulation
insulin
alkalosis

Question 20

stimulates K+ movement out of the cell (4)

Answer 20

a1 stimulation
aldosterone
exercise
acidosis

Question 21

where does K+ reabsorption occur

Answer 21

a-intercalated cells

Question 22

where does K+ secretion occur

Answer 22

principal cells

Question 23

mechanism of K+ reabsorption

Answer 23

H+K+ATPase. Exchange

Question 24

effects of low K+ diet

Answer 24

decreased K+ excretion

Question 25

effects of high K+ diet (3)

Answer 25

increased K+ secretion
increased Na+K+ATPase
increased aldosterone

Question 26

aldosterone’s effects on K+

Answer 26

secretion by Na+K+ATPase

Question 27

modulators of Ca2+ reabsorption (2)

Answer 27

PTH

cAMP

Question 28

sites of isosmotic water absorption in the nephron (2)

Answer 28

early proximal tubule

late proximal tubule

Question 29

dilution segments of nephron (2)

Answer 29

thick ascending limb

early distal tubule

Question 30

water permeability of the late distal tubule & CD (2)

Answer 30

impermeable w/o ADH

permeable to H2O w/ ADH

Question 31

aldosterone’s effects on the collecting duct (3)

Answer 31

increases # of:

1. Na+ channels
2. Na+K+ATPase pumps
3. K+ channels

Question 32

where is carbonic anhydrase activity (2)

Answer 32

early proximal tubule

a-intercalated cells