RENAL AND GU Flashcards

(57 cards)

1
Q

What defines a UTI?

A

> 10^5 organisms/mL or less if with pyuria(pus in the urine)

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2
Q

What can a bladder UTI lead to?

A

cystitis

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3
Q

What is a prostate UTI?

A

Prostatitis

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4
Q

What is a urethra UTI?

A

Urethritis

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5
Q

What is the most common cause of UTIs?

A

E.coli then staph saprophyticus, proteus and klebisella

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6
Q

What are risk factors for UTIs?

A

Diabetes, pregnancy, impaired voiding, sex, stones, intact male foreskin

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7
Q

What organism makes a UTI complicated?

A

S.aureus

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8
Q

What are symptoms of acute pyelonephritis?

A

High fever, rigors, vomiting, loin pain, tenderness

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9
Q

What are symptoms of cystitis?

A

Frequency, dysuria (painful or difficult urnination), urgency, haematuria and suprapubic pain

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10
Q

What are the symptoms of prostatitis?

A

Flu-like, low backache, few urinary symptoms and swollen tender prostate on DRE

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11
Q

What appears on a UTI urine dipstick?

A

Leucocytes and nitrates

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12
Q

Which antibiotics are used for UTIs?

A

Trimethoprim or nitrofurantoin(is eGFR <30)

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13
Q

Where are renal calculi most common?

A

Pelviureteric junction
Pelvic brim
Vesicoureteric junction

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14
Q

Are renal stones more common in males or females?

A

Males

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15
Q

What is the pain like for renal colic?

A

Loin to groin with nausea and vomitting, haem and proteinuria, anuria, sterile pyuria

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16
Q

What foods are linked to kidney stones?

A

Spinach, tea, rhubarb, strawberries, nuts, chocolate

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17
Q

What blood tests do you do for renal stones?

A

Full blood count, U+E, PO4, Glucose, bicarbonate, urate
Imaging- young- xr
Old- non-contrast CT

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18
Q

What is the treatment for renal colic?

A

Pain relief, anti emetics, ccb and extracorporeal shockwave lithotripsy to remove the stone

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19
Q

What type of cancer is bladder cancer?

A

Transitional cell cancinoma

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20
Q

What are signs other than painless haematuria for bladder cancer?

A

Frequency, urgency, dysuria and urinary tract obstruction

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21
Q

What does TURBT stand for?

A

Transurethral resection of bladder tumour

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22
Q

What is the treatment for t2/3 stage bladder cancer?

A

Radical cystectomy or post op chemo

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23
Q

What is treatment foe stage Tis, Ta and T1 bladder cancer?

A

Transurethral Resection of Bladder Tumur and cisplatin

24
Q

What are symptoms of renal cancer?

A

Haematuria, loin pain, abdominal mass, anorexia, high BP from renin

25
What issues are there with treating renal cancer?
It is very radio/chemo resisitant but for T1= surgically whilst the rest are treated with biological therapies
26
What is nephritic syndrome causes?
IgA nephropathy, post streptococcal glomerulonephritis, goodpasture's, vascular disease
27
With Nephritic syndrome do you get hypo or hypertension?
Hypertension
28
What does post-streptococci glomerulonephritis present with?
Group A beta-haemolytic streptococcus
29
What are the causes of nephrotic syndrome?
Minimal change disease, membranous glomerulonephritis- 1st Diabetes melitus, malignancy, HIV, SLR- 2ndry
30
What are signs other than proteinuria for nephrotic syndrome?
Odeama, Hyperlidaemia and hypoalbuminaemia
31
What is minimal change disease?
Where cytokines damage the glomeruli so the podocyte foot processes flatten
32
What is urine retention?
producing urine but not being able to void
33
What are causes of urine retention?
Benign prostate enlargement, prostate cancer, MS or prolapsed disc, drugs blocked catheter
34
What hormone causes prostate hyperplasia?
Dihydrotestosterone
35
What are the treatments for BPH?
Medical= alpha blockers or 5 aplha reductase inhibitors Surgical: Transurethral resection of the prostate retropubic prostatectomy
36
What type of cancer is prostate cancer?
Adenocarcinoma
37
What scoring system is used for prostate cancer and how does it work?
The Gleason's score and it looks at how much the cancer cells look uniform
38
What are treatments for prostate cancer?
Radical prostatectomy, radical radiotherapy, hormone therapy (anti-androgen and LHRH agonists), chemo
39
What investigation shows testicular torsion?
Doppler ultrasound
40
What is epididymo-orchitis?
Sudden onset testicular pain due to STI
41
What are signs of testicular cancer?
A painless lump, haematospermia, abdominal mass
42
What are the 2 types of testicular cancer?
Seminoma or non seminoma
43
What are the 3 tumour markers for testicular cancer?
Alpha fetoprotein Beta human chorionic gonadotrophin Lactate dehydrogenase
44
How do you treat seminomas?
radical orchiectomy and radio
45
How do you treat non-seminomas?
Chemo
46
What genes are asociated with polycystic kidney disease?
PKD1 and PKD 2
47
Causes of renal AKI?
Glomerulonephritis, acute tubular necrosis, drugs, vasculitis
48
What autoantibodies are seen in AKI?
ANCA and anti-GBM
49
What are causes of CKD?
Diabetes, PKD, hypertension, reflux nephropathy, obstructive uropathy
50
What is the eGFR in stage 4 CKD?
15-30
51
Where in the testes is testicular cancer most commonly found?
In the body
52
What is the most common compostition of renal stones?
Calcium oxalate?
53
What is an investigation for renal cancer?
Intravenous urogram
54
What is the most common type of bladder cancer?
Transitional
55
What age group does testicular cancer effect?
20-40
56
What is a hydroceles?
Fluid in the tunica vaginalis that can recover spontanoeously
57
What is a varocele?
A dilated pampiniform plexus which feels like a bag of worms