Renal + Hepatic VHA Flashcards
(35 cards)
reabsorption
refers to tubule to blood direction
secretion
refers to blood to tubule direction
Which arteriole goes towards the glomerulus?
afferent arteriole
brings blood to the glomerulus
fluid flow through nephron tubules (4)
1) proximal tubule
2) loop of henle
3) distal tubule
4) collecting duct
What epithelial lines Bowman’s capsule?
simpel squamous epithelium
Bowman’s space
between glomerulus and Bowman’s capsule
How can you determine vascular pole?
there should 2 two arterioles
Where are proximal tubules found?
more near the urinary tract
What covers the glomerular capillary bed?
visceral epithelium of podocytes
How do podocytes form a barrier?
1) chemical barrier due to high negative charge
2) basement membrane forms physical barrier
Fenestrations
small openings in the capillary walls that prevent blood from getting into filtrate
ex: in hematuria there is a problem since blood is passing through
where is podocyte on stain?
looks like a cell around Bowman’s space
can see the nuclei of the cell
macula densa cells
associated with the distal tubule
secrete renin
What distinguishes a proximal tubule?
proximal tubule has brush border and is thicker
*thicker for more surface area for bulk reabsorption
Do tubules and bowman’s space contain filtrate?
yes to both
Where are mesangial cells?
by distal tubules and vascular pole
which cells comprise the majority of the glomerular filtration barrier?
podocytes
Cortex vs. medulla location
cortex lies outside the medulla
Are there collecting ducts in the cortex?
yes
does fluid flow from glomeruli to distal tubule?
yes! fluid flows from glomeruli to tubules in general
dual blood supply of the liver
1) 25% of oxygenated blood from hepatic artery
2) 75% deoxygenated blood from portal vein (via GI)
portal triad
hepatic artery
portal vein
bile duct
*branches of these throughout the liver
flow of blood through the liver
blood flows from the hepatic artery / portal vein toward the central vein
what does central vein look like in histology?
really just looks like a white opening with some sinusoids flowing towards it