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Pharmacology > Renal & Urinary Drugs > Flashcards

Renal & Urinary Drugs Flashcards

(47 cards)

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1
Q

Furosemide (Lasix, Salix)

A

-Loop diuretic (inhibit tubular reabsorption of Na)
-Rapid onset of action
-Promote excretion of Cl, K, & H2O
-Treats Hypercalcemia nephropathy, uremia
-Reduces edema associated with CHF

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2
Q

Mannitol 20%

A

-Osmotic diuretic (exert osmotic pressure in renal tubules to limit tubular reabsorption)
-Treat oliguric renal failure
-Reduces intraocular & intracranial pressure
-Reduces edema, Ascites

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3
Q

Glycerine

A

-Osmotic diuretic (exert osmotic pressure in renal tubules to limit tubular reabsorption)
-Treat oliguric renal failure
-Reduces intraocular & intracranial pressure
-Reduces edema, Ascites

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4
Q

Chlorothiazide (Diuril)

A

-Thiazide diuretic
-Inhibit reabsorption of Na, Cl, & H2O
-Longer duration of action than loop diuretics
-Treats nephrogenic diabetes insipidus, calcium oxalate uroliths, hypoglycemia, heart failure

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5
Q

Hydrochlorothiazide (HydroDiuril)

A

-Thiazide diuretic
-Inhibit reabsorption of Na, Cl, & H2O
-Longer duration of action than loop diuretics
-Treats nephrogenic diabetes insipidus, calcium oxalate uroliths, hypoglycemia, heart failure

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6
Q

Spironolactone

A

-Potassium-sparing diuretic
-Aldosterone antagonist (enhances excretion of Na & H2O, but not K)
-Reduce edema

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7
Q

Triamterene

A

-Potassium-sparing diuretic
-Aldosterone antagonist (enhances excretion of Na & H2O, but not K)
-Reduce edema

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8
Q

Acetazolamide (Diamox)

A

-Carbonic anhydrase inhibitors
-Incr UOP and excretion of solutes
-Reduce intraocular pressure (inhibits production of aqueous humor)
-Can treat metabolic acidosis

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9
Q

Dichlorphenamide (Daranide)

A

-Carbonic anhydrase inhibitors
-Incr UOP and excretion of solutes
-Reduce intraocular pressure (inhibits production of aqueous humor)

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10
Q

Methazolamide

A

-Carbonic anhydrase inhibitors
-Incr UOP and excretion of solutes
-Reduce intraocular pressure (inhibits production of aqueous humor)

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11
Q

Bethanechol (Urecholine)

A

-Cholinergic agent (direct-acting)
-Treats GI and urinary tract atony

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12
Q

Propantheline

A

-Anticholinergic agent
-Produce muscle relaxation
-Treat urinary incontinence by retaining urine

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13
Q

Butylhyoscine (Buscopan)

A

-Anticholinergic agent
-Produce muscle relaxation
-Treat urinary incontinence by retaining urine

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14
Q

Phenoxybenzamine (Dibenzyline)

A

-Alpha antagonist (relax smooth muscle, decr BP)
-Reduces sphincter tone to treat urinary retention

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15
Q

Nicergoline (Sermion)

A

-Alpha antagonist (relax smooth muscle, decr BP)
-Reduces sphincter tone to treat urinary retention

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16
Q

Prazosin (Minipress)

A

-Alpha antagonist (relax smooth muscle, decr BP)
-Reduces sphincter tone to treat urinary retention
-Reduces BP

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17
Q

Propranolol

A

-Beta antagonist
-Control hypertension associated with CKD

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18
Q

Benazepril (Lotensin, Fortekor)

A

-ACE inhibitor
-Treats hypertension in CKD, CHF, PLE

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19
Q

Captopril (Capoten)

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A

-ACE inhibitor
-Treats hypertension in CKD, CHF, PLE

20
Q

Enalapril (Enacard)

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A

-ACE inhibitor
-Treats hypertension in CKD, CHF, PLE

21
Q

Lisinopril

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A

-ACE inhibitor
-Treats hypertension in CKD, CHF, PLE

22
Q

Ramipril

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A

-ACE inhibitor
-Treats hypertension in CKD, CHF, PLE

23
Q

Hydralazine (Apresoline)

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A

-Vasodilator
-Treats nonresponding hypertension

24
Q

Dopamine (Intropin)

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A

-Vasodilator
-Treats nonresponding hypertension
-Promotes diuresis

25
Diltiazem (Cardizem)
-Calcium channel blocker -Treats nonresponding hypertension
26
Verapamil (Isoptin)
-Calcium channel blocker -Treats nonresponding hypertension
27
Amlodipine (Norvasc)
-Calcium channel blocker -Treats nonresponding hypertension
28
Vasopressin (Pitressin)
-Antidiuretic hormone (ADH) -Treats diabetes insipidus
29
Methionine (Methigel)
-Urinary acidifier (produce uric acid) -Dissolves and prevents structure uroliths Side-effects: -GI upset
30
Ammonium chloride (Uroeze)
-Urinary acidifier (produce uric acid) -Dissolves and prevents structure uroliths Side-effects: -GI upset
31
Allopurinol (Zyloprim)
-Xanthine oxidase inhibitor -Decr production of iron acid -Dissolve ammonium acid irate uroliths
32
Potassium citrate (Urocit-K)
-Urinary alkalizer -Management of ammonium acid irate, calcium oxalate, and cystine urolithiasis
33
Sodium bicarbonate
-Urinary alkalizer -Management of ammonium acid irate, calcium oxalate, and cystine urolithiasis Side-effects: -Electrolyte imbalances
34
Tiopronin (Thiola)
-Urinary alkalizer -Management of ammonium acid irate, calcium oxalate, and cystine urolithiasis
35
Baclofen (Lioresal)
-Muscle relaxer for urinary retention in dogs (do NOT give to cats!) Side-effects: -Sedation -Weakness -Pruritis -Salivation -GI upset
36
Ephedrine sulfate
-Adrenergic agonist -Treats urinary incontinence
37
Estradiol/Estriol (Incurin)
-Short-acting estrogen drugs -Treat urinary incontinence in spayed dogs
38
Flavoxate HCl (Urispas)
-Treats hyperactive bladder and urge incontinence Side-effects: -Weakness
39
Imipramine (Tofranil)
-Tricyclic antidepressant -Treats urinary incontinence Side-effects: -Tachycardia -Hyperexcitability -Tremors
40
Diethylstilbestrol (DES)
-Synthetic estrogen hormone -Treats urinary incontinence in spayed females Side-effects: -Bone marrow suppression
41
Oxybutynin (Ditropan, Oxytrol)
-Genitourinary smooth muscle relaxant -Treats urinary spasms
42
Phenylpropanolamine (Prion)
-Adrenergic agonist -Treats urethral sphincter hypotonus
43
Phenazopyridine
-Urinary tract analgesic -Should not be used in cats (causes methemoglobinemia and Heinz body anemia)
44
Amitriptyline (Elavil)
-Tricyclic antidepressant -Treats interstitial cystitis & FLUTD -Has analgesic properties Side-effects: -Tachycardia -Sedation -Weight gain
45
Pentosan polysulfate sodium (Elmiron)
-Glycosaminoglycan -Reduces transitional cell injury -Treats interstitial cystitis & FLUTD Side-effects: -Vomiting -Anorexia -Lethargy -Bleeding
46
Epakitin
-Nutritional supplement -Reduces phosphorous levels in CKD
47
Azodyl
-Nutritional supplement -Reduces uremic toxins to prevent damage to kidneys

Pharmacology (7 decks)

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