Reproductive Embryology Flashcards Preview

HRM - Anatomy/Embryology/Histology > Reproductive Embryology > Flashcards

Flashcards in Reproductive Embryology Deck (32):
1

Which ridge of the intermediate mesoderm makes the genital system?

Gonadal or genital ridge

2

When is phenotypic sex made manifest?

Seventh week of development

3

What gene is important for male phenotype? What does it produce?

SRY (sex determining region of Y)
Testis-determining factor

4

What is the most common abnormality of sexual differentiation?

Klinefelter syndrome

5

What is the genotype of klinefelter syndrome?

XXY genotype

6

Are people affected by Klinefelter male or female?

Male, with femininization

7

What are the symptoms of turner syndrome?

Short stature
High arched palate
Webbed neck
Shield-like chest
Inverted nipples
Cardiac and renal anomalies

8

What is the genotype of Turner syndrome?

XO 45

9

What genotype do true hermaphrodites have?

XX

10

Where do gametes come from in development?

Umbilical vesicle (yolk sac)

11

Where to gametes migrate to in development?

Genital ridge

12

When does gamete migration happen? (what week)

5th week

13

What do developing gonads consist of?

Mesothelium
Mesenchyme
Primordial germ cells

14

What serve as the precursors to the Sertoli cells?

Cortical cords

15

What do the cortical cords form?

Sertoli cells
Seminiferous tubules
Rete testis
Tubuli recti

16

What do the mesonephric ductules become?

Efferent ductules, then distal epididymis

17

What forms the interstitial cells of Leydig?

Mesenchyme

18

_______ induces Sertoli cells to produce ________, which suppresses development of the ___________ ducts.

hCG induces
Anti-mullerian hormone (Mullerian inhibitor substance)
Paramesonephric (mullerian ducts)

19

What does the indifferent sexual duct system consist of?

Mesonephric ducts (Wolffian)
Paramesonephric ducts (Mullerian)

20

Where do the caudal ends of the paramesonephric ducts fuse?

Urogenital sinus

21

What is the remnant of the paramesonephric duct called in males?

Prostatic utricle

22

What stimulates the mesonephric duct to mature? What does it turn into?

Testosterone from interstitial cells
Epididymis, ductus deferens, ejaculatory duct

23

What stimulates the development of the seminal vesicles? Where does it bud out from?

Testosterone
Ductus deferens

24

What forms the prostate gland?

Epithelial outgrowth of pelvic urogenital sinus

25

What forms the bulbourethral gland?

Epithelial outgrowth of spongy urethra (UG sinus)

26

The absence of this allows paramesonephric duct development?

Anti-mullerian hormone

27

When the two paramesonephric ducts fuse, what forms?

Uterovaginal primordium

28

What forms the upper one-third of the vagina?

Uterovaginal primordium

29

What forms the lower two-thirds of the vagina?

Urogenital sinus

30

What are the female homologues of the bulbourethral glands?

Greater vestibular glands

31

What causes mesonephric ducts to regress?

Lack of testosterone

32

If the mesonephric ducts fail to regress completely in the female, what can result?

Gardner's duct (perhaps cystic)