Research Medicine

Question 1

1. What is biomedical research?
2. Why animal models? (3)
3. LVTs role (2)

Answer 1

1. Broad area of science that looks for ways to prevent & treat diseases that cause illness and death in people and animals.
   - Involves studying biological processes & diseases using various models, including animals.
2. Essential for understanding complex bio systems
   - Bridge the gap between vitro (cell culture) studies and human clinical trials
   - Crucial for drug development, vax testing, & understanding disease pathogenesis
3. LVT role
   - Integral scientific partners!
   - Ensure animal welfare, data integrity, & regulatory compliance

Question 2

Three R’s of the Foundation of Research in research medicine
*LVTs adhere to these!

Answer 2

Reduce: Number of animals used.
Refine: Tests to cause animals less stress.
Replace: Animal studies with other methods.

Question 3

LVT Responsibilities (3)

Answer 3

1. Daily animal husbandry
   - Providing appropriate housing, nutrition, and environmental enrichment.
   - Monitoring animal health and behavior for subtle changes.
2. Preventative health care
   - Meds, vax, para control
   - Assisting with routine physicals & wellness testing.
3. Recognizing & alleviating pain/distress
   - Identify these signs
   - Implement analgesic & supportive care protocols
   - Provide environmental enrichment, QOL assessment/care.