Respiratory system Flashcards

(71 cards)

1
Q

Ventilation

A

RR X TV

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2
Q

What is this?

A

Alveoli

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3
Q

What is this?

A

Bronchioles

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4
Q

What is this?

A

Bronchus

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5
Q

What is this?

A

Diaphragm

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6
Q

What is this?

A

Larynx

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7
Q

What is this?

A

Lung

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8
Q

What is this?

A

Nasal Cavity

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9
Q

What is this?

A

Pharynx

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10
Q

What is this?

A

Trachea

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11
Q

function of the alveoli

A

To exchange oxygen and carbon dioxide molecules to and from the bloodstream

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12
Q

function of the bronchioles

A

To provide a pathway for air between bronchus and alveoli

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13
Q

function of the Bronchi

A

To provide a pathway for air between trachea and bronchioles

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14
Q

function of the trachea

A

To provide a pathway for air between the larynx and the bronchus

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15
Q

function of the nose/nasal cavity

A

To warm, moisten and filter air entering the respiratory system

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16
Q

three functions of the pharynx

A

To provide passageway for food and air

To warm, moistens and protects from infection (mucous membrane)

To assists with speech
Involved with hearing (nasopharynx)

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17
Q

function of the larynx

A

To allow air to pass through to the trachea whilst stopping food and liquids from entering the respiratory tract
To house the vocal cords which manipulate pitch and volume essential for sound and speech

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18
Q

components of the upper respiratory system (Anatomically)

A

Nasal cavity
Oral cavity
Pharynx
Larynx

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19
Q

components of the lower respiratory system (Anatomically)

A

Trachea
Bronchi
Bronchioles
Alveoli
Lungs

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20
Q

function of the pleura

A

to provide lubrication, reducing friction during the movement of lungs during breathing

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21
Q

respiration

A

movement of air/oxygen from external environment to the cells of the body

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22
Q

Expiration

A

Diaphragm domes and intercostal muscles relax moving ribcage down and in

Elastic lung tissue recoils decreaing thoracic volume and increasing intrathoracic pressure

Air is expelled and pushed out of the lungs

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23
Q

the right lug contains how many lobes?

A

3

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24
Q

Gaseous exchange at the lungs

A

O2 : alveoli β€”> lungs
CO2 : blood β€”> alveoli

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25
Inhalation
Diaphragm flattens and intercostal muscles contract moving ribcage up and out Visceral pleura is pulled outward increasing thoracic volume and decreasing intrathoracic pressure Air is sucked into the lungs
26
The Respiration Processes
1. Pulmonary Ventilation (Respiratory System) - inspiration, and expiration 2. External Respiration (Respiratory System) - O2 diffuses from the lungs to the blood - CO2 diffuses from the blood to the lungs 3. Transport of Respiratory Gases (Cardiovascular System) - CV system transports gases using blood. - O2 is transported from lungs to tIssue - CO2 is transported from tissue to lungs 4. Internal Respiration (Cardiovascular System) - O2 diffuses from blood to tissue cells - CO2 diffuses from the tissue cells to blood
27
Conducting Zone (Functionaly)
Moves air into and out of the lungs Nose, mouth, pharynx, larynx, trachea, bronchus
28
Respiratory Zone (Functionaly)
Moves the respiratory gases in and out of the blood Bronchioles, alveoli
29
Gas Exchange in Alveoli
Oxygen flows from the alveoli into the blood Carbon dioxide flows from the blood into the alveoli
30
Respiratory Membrane
- made up of alveolar epithelial cells, and the pulmonary capillary endothelial cell. - The membrane has a large, thin and permeable surface. - Gas particles can be exchanged quickly, and in large volumes
31
Respiratory Membrane Squamous Type 1 Alveolar Cells
- Allow for rapid gas diffusion between the air and blood - Major cell type on alveolar surface (95% Surface Area covered)
32
Respiratory Membrane Round/Cuboidal Type II Alveolar Cells
Repair the alveolar epithelium when squamous cells are damaged - To secrete pulmonary surfactant - Outnumber the alveolar cells - Covers about 5% of the surface area
33
Respiratory Membrane Alveolar Macrophages
- Clearing up debris through phagocytosis - Most abundant
34
Tidal Volume (TV)
Amount of air inhaled or exhaled with each breath under resting conditions
35
Inspiratory Reserve Volume (IRV)
Amount of air that can be forcefully inhaled after a normal tidal volume inspiration
36
Expiratory Reserve Volume (ERV)
Amount of air that can be forcefully exhaled after a normal tidal volume expiration
37
Residual Volume (RV)
Amount of air remaining in the lungs after a forced expiration
38
Vital Capacity (VC)
Maximum amount of air that can be expired after a maximum inspiratory effort VC= TV+IRV+ERV
39
Inspiratory Capacity (IC)
Maximum amount of air that can be inspired after a normal tidal volume expiration IC=TV+IRV
40
Functional Residual Capacity (FRC)
Volume of air remaining in the lungs after a normal tidal volume expiration FRC=ERV+RV
41
Total Lung Capacity (TLC)
Maximum amount of air contained in lungs after a maximum inspiratory effort TLC=TV+IRV+ERV+RV
42
Forced Vital Capacity (FVC)
Gas forcibly expelled after taking a deep breath
43
Forced Expiratory Volume In 1 Second
The Amount Of Air which can be forcefully exhaled in 1 second. Normally about 75% of FVC. FEV1/FVC
44
Minute Ventilation (MV)
The total amount of gas flow into or out of the respiratory tract in one minute 𝑀𝑉(π‘šπΏ/π‘šπ‘–π‘›) = π΅π‘Ÿπ‘’π‘Žπ‘‘h𝑠 π‘π‘’π‘Ÿ π‘šπ‘–π‘›π‘’π‘‘π‘’ Γ— π‘‡π‘–π‘‘π‘Žπ‘™ π‘‰π‘œπ‘™π‘’π‘šπ‘’ DOES NOT ACCOUNT FOR DEAD SPACE
45
Alveolar Ventilation Rate (AVR)
Flow of gases into and out of the alveoli (gas exchange areas) in one minute accounts for dead space AVR units in mL/min 𝐴𝑉𝑅 = π΅π‘Ÿπ‘’π‘Žπ‘‘h𝑠 π‘π‘’π‘Ÿ π‘šπ‘–π‘›π‘’π‘‘π‘’ Γ— (π‘‡π‘–π‘‘π‘Žπ‘™ π‘‰π‘œπ‘™π‘’π‘šπ‘’ βˆ’ π·π‘’π‘Žπ‘‘ π‘†π‘π‘Žπ‘π‘’)
46
Anatomical Dead Space
Inspired air that does not contribute to gas exchange in the alveoli, lost in travel (approximately 150 mL)
47
Obstructive Lung Diseases
Obstructive lung disease is caused by a narrowing of pulmonary airways leading to increased resistance to air flow. Can make it harder to exhale all the air in the lungs - Significant decrease FEV1 - TLC, FRC, RV, FVC may increase
48
Restrictive Lung Diseases
Restrictive lung disease is characterised by increased stiffness and limited expansion of the lungs - Small decrease in FEV1 - Significant fall (decline) in Forced Vital Capacity, Residual Volume, Functional Residual Capacity, TLC. - FEV1/FVC ratio can be higher than normal
49
hyperventilation
Rapid, deep breathing pushes reaction to the LEFT by β€œblowing off ” CO2 (CO2 decreases), causing pH to increase (BASIC) (hydrogen ions decreasing) CO2 (expired) + H2O ← H2CO3 ← HCO3- + H+
50
hypoventilation
Rapid, shallow breathing pushes reaction to the RIGHT by allowing CO2 to accumulate in the blood, causing pH to decrease (ACIDIC) (hydrogen ions increasing) CO2 + H2O β†’ H2CO3 β†’ HCO3- + H+
51
Partial pressure
- the pressure that a particular gas exerts in a gas mixture - caused by the impact of molecules against each other or against surrounding surfaces. - Gases move from higher pressures to lower Pressure allowing gases to move from one fluid compartment into another throughout the body.
52
What is A?
Forced vital capacity (FVC)
53
What is B?
Inspiratory reserve volume (IRV)
54
What is C?
Tidal volume
55
What is D?
Expiratory reserve volume (ERV)
56
What is E?
Residual volume (RV)
57
What is F?
Inspiratory capacity (IC)
58
What is G?
Functional residual capacity (FRC)
59
What is H?
Vital capacity (VC)
60
What is I?
Total lung capacity (TLC)
61
What is J?
Residual volume (RV)
62
Chemoreceptors
Detect chemical changes in the blood (specifically carbon dioxide, pH and oxygen)
63
Central Chemoreceptors
- Located throughout the brainstem and the medulla (medulla oblongata) Detects: - Decrease in pH (increase in hydrogen ions) - Increase in carbon dioxide Signals - Increases respiration - Increases oxygen intake - Decreases carbon dioxide expiration
64
Peripheral Chemoreceptors
- Located in carotid and aortic body Detects: - Decrease in pH (increase in hydrogen ions) - Increase in carbon dioxide - Decrease in oxygen Signals: (Medullary centres) - Respiration increases
65
2 major pathways for oxygen transport in the blood
- (98.5%) Loosely bound to haemoglobin (Hb) in RBCs [Bound to the heme part of haemoglobin]. - (1.5%) Dissolved in plasma
66
Oxyhaemoglobin
Bright Red Haemoglobin saturated with oxygen 𝐻𝐻𝑏 + 𝑂2↔𝐻𝑏𝑂2 + 𝐻+
67
Deoxyhemoglobin
Purplish Blue Unsaturated 𝐻𝐻𝑏 + 𝑂2↔𝐻𝑏𝑂2 + 𝐻+
68
Oxygen Dissociation Curve Axis
- Y-Axis: How much oxygen is bound to haemoglobin - X-Axis: Relative amount (partial pressure) dissolved in fluid surrounding haemoglobin
69
The oxygen dissociation curve shifts to the right when there is
- An Increase in body temperature. (Binding affinity for oxygen decreases, promoting the release of oxygen) (Occurs in cells) - An increase in carbon dioxide - An decrease in pH (Increase in hydrogen ions) - Increased pCO2 (partial pressure) levels - Decreased Tissue pO2 Results in an Increase of oxygen release, and decrease in haemoglobin saturation.
70
The Oxygen dissociation curve shifts to the left when there is
- Decrease in body temperature - Decrease in carbon dioxide levels - Increase in pH levels - Decreased pCO2 (partial pressure) levels - Increased tissue pO2 levels Results in an decrease of oxygen release, and increase in haemoglobin saturation
71
3 pathways for Carbon Dioxide Transport
1. (7-10%) Dissolved in the plasma 2. (20%) Binds to haemoglobin forming carbaminohemoglobin 𝐢𝑂2 + 𝐻𝑏 βŸ·π»π‘πΆπ‘‚2 - Reaction is rapid and does not require a catalyst - Carbon dioxide does not compete with oxyhemoglobin transport as it binds to the amino acids of globin rather than the heme 3. (70%) transported as bicarbonate ions (HCO3-) in plasma