Resus in special circumstances Flashcards
(170 cards)
What can cause life-threatening cardiac arrhythmias or cardiorespiratory arrest?
Electrolyte abnormalities
Which electrolyte disorder is most commonly associated with life-threatening arrhythmias?
Hyperkalaemia
Define hyperkalaemia.
A serum potassium concentration > 5.5 mmol L-1
What are the main causes of hyperkalaemia?
- Renal failure
- Drugs (e.g. ACE-I, ARB)
- Tissue breakdown (e.g. rhabdomyolysis)
- Metabolic acidosis
- Endocrine disorders
- Diet
- Spurious (pseudo-hyperkalaemia)
What are common symptoms of hyperkalaemia?
Weakness, flaccid paralysis, paraesthesia, depressed deep tendon reflexes
What ECG changes are associated with hyperkalaemia?
- First degree heart block
- Flattened or absent P waves
- Tall, peaked T waves
- ST-segment depression
- S and T wave merging
- Widened QRS
- Ventricular tachycardia
- Bradycardia
- Cardiac arrest
What are the five key steps in treating hyperkalaemia?
- Cardiac protection
- Shifting potassium into cells
- Removing potassium from the body
- Monitoring serum potassium concentration
- Prevention of recurrence
What is the definition of hypokalaemia?
A serum potassium level < 3.5 mmol L-1
What are the main causes of hypokalaemia?
- Gastrointestinal loss
- Drugs (e.g. diuretics)
- Renal losses
- Endocrine disorders
- Metabolic alkalosis
- Magnesium depletion
- Poor dietary intake
What are some ECG features of hypokalaemia?
- U waves
- T wave flattening
- ST segment changes
- Arrhythmias, especially with digoxin
- Cardiac arrest
What is the maximum recommended IV dose of potassium?
20 mmol h-1
What should be done during IV potassium infusion?
Continuous ECG monitoring is essential
What modifications to CPR are recommended in the presence of severe hyperkalaemia?
- Confirm hyperkalaemia
- Protect the heart with calcium chloride
- Shift potassium into cells with glucose/insulin
- Administer sodium bicarbonate if severe acidosis
- Consider dialysis for hyperkalaemic cardiac arrest resistant to treatment
What is the most common cause of death in haemodialysis patients?
Sudden cardiac death
What should be done if cardiac arrest occurs during haemodialysis?
- Call the resuscitation team
- Start standard ALS protocols
- Stop ultrafiltration and give a fluid bolus
- Disconnect from the dialysis machine
What are the causes of hypercalcaemia?
- Primary or tertiary hyperparathyroidism
- Malignancy
- Sarcoidosis
- Drugs
What are the presentations of hypercalcaemia?
- Confusion
- Weakness
- Abdominal pain
- Hypotension
- Arrhythmias
- Cardiac arrest
What ECG changes are associated with hypercalcaemia?
- Short QT interval
- Prolonged QRS interval
- Flat T waves
- AV block
- Cardiac arrest
What is the treatment for hypercalcaemia?
- Fluid replacement IV
- Furosemide 1 mg kg-1 IV
- Hydrocortisone 200–300 mg IV
- Pamidronate 30–90 mg IV
- Treat underlying cause
What is the total calcium level that indicates hypocalcaemia?
< 2.1 mmol L-1
What are the causes of hypocalcaemia?
- Chronic renal failure
- Acute pancreatitis
- Calcium channel blocker overdose
- Toxic shock syndrome
- Rhabdomyolysis
- Tumour lysis syndrome
What are the presentations of hypocalcaemia?
- Paraesthesia
- Tetany
- Seizures
- AV block
- Cardiac arrest
What ECG changes are associated with hypocalcaemia?
- Prolonged QT interval
- T wave inversion
- Heart block
- Cardiac arrest
What is the treatment for hypocalcaemia?
- Calcium chloride 10% 10–40 mL IV
- Magnesium sulfate (2–4 mL: 4–8 mmol) IV if necessary