Review

Question 1

Bacteria can become resistant to antibiotics through DNA mutations or plasmid transfer. What are 3 other ways that antibiotic resistance can develop

Answer 1

1. Improper use
2. Cross resistance
3. Nosocomial organisms

Question 2

5 possible mechanisms thru which antibiotics kill or inhibit the growth of bacteria

Answer 2

1. Inhibit cell wall growth
2. Damage cell membrane
3. Inhibit protein synthesis
4. Anti metabolites
5. Impair nucleic acids (DNA)

Question 3

Penicillin mechanism

Answer 3

Inhibit cell wall growth

Question 4

Natural Penicillins (G & V) are narrow spectrum and mostly target gram ___________ bacteria

Answer 4

Positive (have a cell wall)

Question 5

What is a caution when using penicillin

Answer 5

Allergy or anaphylaxis

Question 6

Penicillin G can only be given…

Answer 6

Parenterally

Question 7

Penicillin ______ can be given enterally

Answer 7

V

Question 8

Amoxicillin
Ampicillin
Hetacillin
Carbenicillin
Ticarcillin
Piperacillin

Answer 8

Broad Spectrum Semisynthetic Penicllins

Question 9

What type of bacteria do broad spectrum semisynthetic penicillins target?

Answer 9

Gram + and Gram - bacteria as long as the bacteria does not produce beta-lactamase

Question 10

Cephalosporins are similar to ______________ since they both have a beta-lactam ring

Answer 10

Penicillins